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Current Analytical Chemistry

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ISSN (Print): 1573-4110
ISSN (Online): 1875-6727

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Mini-Review Article

Metal Nanocomposites Based Electrochemical Sensor Platform for Few Emerging Biomarkers

Author(s): Govindhan Maduraiveeran*

Volume 18, Issue 5, 2022

Published on: 17 November, 2020

Page: [509 - 517] Pages: 9

DOI: 10.2174/1573411016999201117094213

Price: $65

Abstract

The design of high-performance electrochemical sensor and biosensor platforms has attracted much interest for the sensitive and selective detection of emergent biomarkers. The electrochemical sensor offers numerous advantageous features including cost-effectiveness and ease of miniaturization, rapid and online monitoring, simultaneous detection ability, etc., which have captivated the potential interdisciplinary research. In this review, the advances and challenges towards the electrochemical detection of emergent biomarkers such as hydrogen peroxide, nitric oxide, β- nicotinamide adenine acetaminophen, dinucleotide (NADH) in biofluids are highlighted based on the recent research outcomes. In fact, the effective utility and benefits of transition metal nanocomposites without the utilization of biological materials, including enzymes, antibodies, etc., as electrode materials towards the detection of selected biomarkers in practical biofluids, monitoring early-stage and diagnosis of disease related biomarkers, are also described. These promising metal nanomaterials based electrochemical sensor platforms concrete the tactic for a new generation of sensing devices.

Keywords: Biomarkers Detection, Electrochemical Sensor, Nanomaterials, Modified Electrode, Biomedical Application, hydrogen peroxide.

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