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Current Medicinal Chemistry


ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Review Article

The Potential Clinical Properties of Magnesium

Author(s): Guido Crisponi*, Valeria Marina Nurchi, Rosita Cappai, Maria Antonietta Zoroddu, Clara Gerosa, Monica Piras, Gavino Faa and Daniela Fanni*

Volume 28 , Issue 35 , 2021

Published on: 16 November, 2020

Page: [7295 - 7311] Pages: 17

DOI: 10.2174/0929867327999201116195343

Price: $65


A significant percentage of costs in pharmaceutical markets is devoted to supplements due to the confidence of consumers in the beneficial effects of these products. Magnesium is one of the supplements with enduring and increasing popularity. According to what is reported online, this metal ion can cure or prevent almost all kinds of diseases. This review aims at illustrating a series of scientifically demonstrated cases in which magnesium was used in clinical practice. Except for its ordinary use as antacid and laxative, other ascertained uses, reported in scientific literature, consist of helping to treat several diseases such as nocturnal leg cramps, pre-eclampsia, diabetes, depression, Parkinson’s and Alzheimer’s disease, hypertension, some types of arrhythmias, asthma, migraine headaches, epilepsy, cerebral haemorrhage, and stroke.

However, many of these promising uses of magnesium require further studies to define the involved molecular mechanisms which should help establishing its uses in relation to the prolonged use of supplements.

Keywords: Magnesium, diabetes, depression, hypertension, migraine headache, preeclampsia, asthma.

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