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Current Organic Synthesis

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ISSN (Online): 1875-6271

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Review Article

Recent Advances in the Synthesis of Pyrazole Derivatives

Author(s): Cheriya Mukkolakkal Abdulla Afsina, Thaipparambil Aneeja, Mohan Neetha and Gopinathan Anilkumar*

Volume 18, Issue 2, 2021

Published on: 09 November, 2020

Page: [197 - 213] Pages: 17

DOI: 10.2174/1570179417666201109151036

Price: $65

Abstract

Pyrazole and its derivatives have gained wide attention in pharmaceutical, agrochemical and biological fields as well as in industry. They exhibit various biological activities such as anti-pyretic, anti-microbial, anti- inflammatory, anti-tumor, anti-viral, anti-histaminic, anti-convulsant, fungicidal, insecticidal, etc. In this review, we summarise the recent advances in the synthesis of pyrazole derivatives using various methodologies and covers literature from 2017-2020.

Keywords: Pyrazole, heterocycle, hydrazine, phenylhydrazine, tosylhydrazine, hydrazone.

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Graphical Abstract

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