Generic placeholder image

Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Research Article

Ag(I)-promoted Decarboxylative Annulation of α-Oxocarboxylic Acids with (E)-3-(2-aminophenyl)-1-Phenylprop-2-en-1-ones Toward 3,4- Functionalized Quinolines

Author(s): Xiaodong Fan, Chang Wang and Jiang Cheng*

Volume 18 , Issue 10 , 2021

Published on: 06 November, 2020

Page: [777 - 782] Pages: 6

DOI: 10.2174/1570178617999201106141315

Price: $65


An efficient Ag-promoted decarboxylative cyclization of α-oxocarboxylic acids with (E)-3- (2-aminophenyl)-1-phenylprop-2-en-1-ones has been developed to afford a series of functionalized quinolines in moderate to good yields. This method was compatible with a variety of functional groups and provided an attractive method toward phenyl(2-phenylquinolin-3-yl)methanones.

Keywords: α-oxocarboxylic acids, (E)-3-(2-aminophenyl)-1-phenylprop-2-en-1-ones, Ag-promoted, decarboxylative cyclization, intramolecular 6π-electrocyclization, quinolines derivatives.

Graphical Abstract

Rights & Permissions Print Export Cite as
© 2022 Bentham Science Publishers | Privacy Policy