摘要
组织工程受细胞和聚合物使用的支配。 细胞可以被认为是要靶向的组织的类型,而聚合物可以是天然的也可以是合成的。 天然聚合物具有诸如非免疫原性和复杂结构的优点,与合成聚合物相比,其有助于形成键。 使用聚合物和细胞,例如纳米颗粒,水凝胶,纳米纤维和微球,已经制备了各种靶向药物递送系统。 支架的设计取决于所用材料对人体的负面影响,它们是使用表面改性技术或新材料合成制备的。 真皮替代品是一个独特的产品系列,旨在通过移植或其他方式替代皮肤部位。 这篇综述着重于生物材料在组织工程中的应用。 该文章应提供天然衍生的脚手架和真皮替代品的鸟瞰图。
关键词: 脚手架,皮肤替代品,组织工程,水凝胶,天然聚合物,纳米纤维。
Current Drug Targets
Title:Biopolymer-based Scaffolds for Tissue Engineering Applications
Volume: 22 Issue: 3
关键词: 脚手架,皮肤替代品,组织工程,水凝胶,天然聚合物,纳米纤维。
摘要: Tissue engineering is governed by the use of cells and polymers. The cells may be accounted for the type of tissue to be targeted, while polymers may vary from natural to synthetic. The natural polymers have advantages such as non-immunogenic and complex structures that help in the formation of bonds in comparison to the synthetic ones. Various targeted drug delivery systems have been prepared using polymers and cells, such as nanoparticles, hydrogels, nanofibers, and microspheres. The design of scaffolds depends on the negative impact of material used on the human body and they have been prepared using surface modification technique or neo material synthesis. The dermal substitutes are a distinctive array that aims at the replacement of skin parts either through grafting or some other means. This review focuses on biomaterials for their use in tissue engineering. This article shall provide the bird's eye view of the scaffolds and dermal substitutes, which are naturally derived.
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Cite this article as:
Biopolymer-based Scaffolds for Tissue Engineering Applications, Current Drug Targets 2021; 22 (3) . https://dx.doi.org/10.2174/1389450121999201102140408
DOI https://dx.doi.org/10.2174/1389450121999201102140408 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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