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Current Medical Imaging


ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

Case Report

Primary Breast Angiosarcoma: Utilisation of Pre-surgical Magnetic Resonance Imaging (MRI) for Accurate Tumour Characterization and Planning – A Case Report and Literature Review

Author(s): Nazimah Ab Mumin*, Kartini Rahmat*, Marlina Tanty Ramli Hamid, Wei Lin Ng, Wai Yee Chan, Xin Ying Cheah, Mee Hoong See and Cheng Har Yip

Volume 17, Issue 4, 2021

Published on: 07 October, 2020

Page: [552 - 558] Pages: 7

DOI: 10.2174/1573405616666201007161119

Price: $65


Background: Primary breast angiosarcoma is a rare malignancy with non-specific clinical and radiological findings.

Case Report: A 30-year-old lady presented with left breast pain and lumpiness for over one year. She has had several breast ultrasounds (US) and was treated for acute mastitis and abscess. Subsequently, in view of the rapid growth of the lump and worsening pain, she was re-investigated with US, elastography, digital breast tomosynthesis (DBT) and MRI. MRI raised the suspicion of angiosarcoma. The diagnosis was confirmed after biopsy and she underwent mastectomy.

Discussion: Literature review on imaging findings of breast angiosarcoma, especially on MRI, is discussed. MRI features showed heterogeneous low signal intensity on T1 and high signal intensity on T2. Dynamic contrast enhancement (DCE) features included either early enhancement with or without washout in the delayed phase, and some reported central areas of non-enhancement.

Conclusion: This case report emphasises on the importance of MRI in clinching the diagnosis of breast angiosarcoma, and hence, should be offered sooner to prevent diagnostic delay.

Keywords: Breast angiosarcoma, magnetic resonance imaging (MRI), ultrasound elastography, digital breast tomosynthesis( DBT), primary breast angiosarcoma, breast cancer.

Graphical Abstract
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