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Current Pharmaceutical Biotechnology


ISSN (Print): 1389-2010
ISSN (Online): 1873-4316

Review Article

Biologically Active Antimicrobial Compounds from Marine Microorganisms (2005-2019)

Author(s): Krishna Muddukrishnaiah, K. Akilandeswari*, Sunnapu Prasad and V.P. Shilpa

Volume 22, Issue 8, 2021

Published on: 29 September, 2020

Page: [1046 - 1060] Pages: 15

DOI: 10.2174/1389201021666200929123040

Price: $65


Introduction: The increase in contagious diseases like nosocomial infections, urinary tract infections, and meningitis has led to the emergence of antimicrobial resistance urgently needs new antimicrobial medication with new modes of action. Some of the antibiotics present in the market have been obtained from terrestrial plants, or extracted semisynthetically from materials which can be fermented.

Methods: Marine microorganisms account for approximately 80% of sea biomass. They are essential for the survival and well-being of aquatic habitats due to their indispensable contribution to biogeochemical cycles and biological processes. In marine ecosystems, microorganisms live as microbial communities in seawater, where symbiotic relationships are formed, and their ecological functions are fulfilled.

Results: Marine microorganisms remain the largest, most diverse and most exciting source of structurally and functionally complex antimicrobial agents. They are extremely involved in their structure and functions. Enormous biological wealth lies in marine habitats. These microorganisms are potential sources of novel antimicrobial compounds to combat the most infectious diseases like nosocomial infections, and urinary tract infections.

Conclusion: This study deals with biologically active antimicrobial compounds taken from marine microorganism source, which was reported between the years 2005 and 2019. This review highlights their chemical groups, their bioactivities and sources. Marine microorganism exploitation techniques have also been reported by the authors.

Keywords: Antimicrobial-resistant, marine environment, marine bacteria, marine fungi, antimicrobial agents, biogeochemical cycles.

Graphical Abstract
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