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Current Topics in Medicinal Chemistry


ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

Review Article

Synthesis and Biological Activity Study of Tanshinone Derivatives: A Literature and Patent Review

Author(s): He Huang, Chuanjun Song* and Junbiao Chang

Volume 20 , Issue 28 , 2020

Page: [2520 - 2534] Pages: 15

DOI: 10.2174/1568026620666200922115109

Price: $65


Tanshinones are a class of bioactive compounds present in the Chinese herbal medicine Danshen (Salvia miltiorrhiza Bunge), containing among others, abietane diterpene quinone scaffolds. Chemical synthesis and biological activity studies of natural and unnatural tanshinone derivatives have been reviewed in this article.

Keywords: Danshen, Tanshinone, Chemical synthesis, Structural modification, Biological activity, Herbal medicine.

Graphical Abstract
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