Abstract
Microwave-assisted organic synthesis is an enabling technology that has been exploited for a variety of applications including medicinal chemistry/drug discovery projects where speed is often a critical factor. In this review, applications of microwave-assisted organic synthesis employing a parallel processing regime are summarized. Examples include parallel synthesis in domestic microwave ovens, the use of specialized multivessel rotors and microtiter plates in dedicated multimode microwave reactors, and applications of SPOT synthesis on cellulose matrices.
Keywords: Parallel synthesis, microwave irradiation, multivessel rotors, microtiter plates, high-throughput synthesis
Combinatorial Chemistry & High Throughput Screening
Title: Parallel Processing of Microwave-Assisted Organic Transformations
Volume: 10 Issue: 9
Author(s): C. Oliver Kappe and Mitra Matloobi
Affiliation:
Keywords: Parallel synthesis, microwave irradiation, multivessel rotors, microtiter plates, high-throughput synthesis
Abstract: Microwave-assisted organic synthesis is an enabling technology that has been exploited for a variety of applications including medicinal chemistry/drug discovery projects where speed is often a critical factor. In this review, applications of microwave-assisted organic synthesis employing a parallel processing regime are summarized. Examples include parallel synthesis in domestic microwave ovens, the use of specialized multivessel rotors and microtiter plates in dedicated multimode microwave reactors, and applications of SPOT synthesis on cellulose matrices.
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Cite this article as:
Kappe Oliver C. and Matloobi Mitra, Parallel Processing of Microwave-Assisted Organic Transformations, Combinatorial Chemistry & High Throughput Screening 2007; 10 (9) . https://dx.doi.org/10.2174/138620707783018496
DOI https://dx.doi.org/10.2174/138620707783018496 |
Print ISSN 1386-2073 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5402 |
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