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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Review Article

Molecular Hydrogen Application in Stroke: Bench to Bedside

Author(s): Lei Huang, Cameron Lenahan, Warren Boling, Jiping Tang and John H. Zhang*

Volume 27, Issue 5, 2021

Published on: 17 September, 2020

Page: [703 - 712] Pages: 10

DOI: 10.2174/1381612826666200917152316

Price: $65

Abstract

Stroke is a major cause of mortality and morbidity worldwide. Effective treatments are limited. Molecular hydrogen is emerging as a novel medical gas with therapeutic potential for various neurological diseases, including stroke. We reviewed the experimental and clinical findings of the effects of molecular hydrogen therapy in stroke patients and models. The underlying neuroprotective mechanisms against stroke pathology were also discussed.

Keywords: Ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage, hydrogen gas, hydrogen-rich saline, hydrogen-rich water, antioxidant, neuroprotection.


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