Abstract
Novel coronavirus (SARS-CoV-2) can infect the respiratory tract and cause severe respiratory syndrome. The excessive inflammatory response is involved in the pathogenicity of the SARS-CoV-2. Symptoms of SARS-CoV-2 are generally associated with immunopathogenesis and may result in pulmonary tissue damage. Melatonin is a natural and multifunctional hormone that is involved in both physiological and pathological conditions in the body, such as immune modulation, anti-inflammation, and antioxidant. Melatonin is found in foods, animal and human milk and increases the expression of anti-inflammatory cytokines and, as an adjuvant treatment in SARS-- CoV-2 infection, it may have considerable therapeutic potential, because of its safety and immunomodulatory effects.
Keywords: Melatonin, SARS-CoV-2, treatment, anti-inflammatory, immunomodulator, natural.
The Natural Products Journal
Title:Melatonin Could Be Beneficial in SARS-CoV-2 Therapy
Volume: 11 Issue: 5
Author(s): Sanaz Baghban Rahimi and Ahmad Hosseinzadeh Adli*
Affiliation:
- Department of Microbiology, Tabriz University of Medical Sciences, Tabriz,Iran
Keywords: Melatonin, SARS-CoV-2, treatment, anti-inflammatory, immunomodulator, natural.
Abstract: Novel coronavirus (SARS-CoV-2) can infect the respiratory tract and cause severe respiratory syndrome. The excessive inflammatory response is involved in the pathogenicity of the SARS-CoV-2. Symptoms of SARS-CoV-2 are generally associated with immunopathogenesis and may result in pulmonary tissue damage. Melatonin is a natural and multifunctional hormone that is involved in both physiological and pathological conditions in the body, such as immune modulation, anti-inflammation, and antioxidant. Melatonin is found in foods, animal and human milk and increases the expression of anti-inflammatory cytokines and, as an adjuvant treatment in SARS-- CoV-2 infection, it may have considerable therapeutic potential, because of its safety and immunomodulatory effects.
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Cite this article as:
Rahimi Baghban Sanaz and Adli Hosseinzadeh Ahmad*, Melatonin Could Be Beneficial in SARS-CoV-2 Therapy, The Natural Products Journal 2021; 11 (5) . https://dx.doi.org/10.2174/2210315510999200905130902
DOI https://dx.doi.org/10.2174/2210315510999200905130902 |
Print ISSN 2210-3155 |
Publisher Name Bentham Science Publisher |
Online ISSN 2210-3163 |
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