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Current Cancer Therapy Reviews


ISSN (Print): 1573-3947
ISSN (Online): 1875-6301

Mechanisms of Intrinsic and Acquired Resistance to EGFR Inhibitors

Author(s): Floriana Morgillo, Giampaolo Tortora and Fortunato Ciardiello

Volume 3, Issue 4, 2007

Page: [276 - 283] Pages: 8

DOI: 10.2174/157339407782496988

Price: $65


In the last decades the epidermal growth factor receptor (EGFR), which is frequently expressed in a variety of epithelial tumors, has been a major target of molecular anticancer therapy.

Keywords: EGFR, Monoclonal antibody, Tyrosine kinase inhibitor, resistance

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