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Current Medicinal Chemistry


ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Review Article (Mini-Review)

Recent Research on Flavonoids and their Biomedical Applications

Author(s): Kangmei Wen, Xiaochuan Fang, Junli Yang, Yongfang Yao, Kutty Selva Nandakumar, Mohamed Labib Salem and Kui Cheng*

Volume 28 , Issue 5 , 2021

Published on: 13 July, 2020

Page: [1042 - 1066] Pages: 25

DOI: 10.2174/0929867327666200713184138

Price: $65


Flavonoids, commonly found in various plants, are a class of polyphenolic compounds having a basic structural unit of 2-phenylchromone. Flavonoid compounds have attracted much attention due to their wide biological applications. In order to facilitate further research on the biomedical application of flavonoids, we surveyed the literature published on the use of flavonoids in medicine during the past decade, documented the commonly found structures in natural flavonoids, and summarized their pharmacological activities as well as associated mechanisms of action against a variety of health disorders including chronic inflammation, cancer, cardiovascular complications and hypoglycemia. In this mini-review, we provide suggestions for further research on the biomedical applications of flavonoids.

Keywords: Anti-inflammatory, antitumor, antiviral, cardiovascular effects, flavonoid, NF-κB.

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