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Letters in Organic Chemistry


ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Letter Article

Convenient Synthesis of 2,4-disubstituted Chromeno[4,3-b]Pyridine by Microwave-Assisted, One- Pot, Three-Component Protocol

Author(s): Ghanshyam Jadhav, Vijay Medhane* and Dattatray Deshmukh

Volume 18, Issue 11, 2021

Published on: 30 June, 2020

Page: [862 - 866] Pages: 5

DOI: 10.2174/1570178617999200630125810

Price: $65


Herein, an efficient and scalable synthesis of 2,4-diaryl substituted chromene [43-b] pyridine derivatives, using a multicomponent reaction strategy by microwave irradiation of 4-amino 2-oxo- 2H-chromene, aromatic aldehydes, and substituted anilines is described. This synthetic strategy was found to be very useful as it follows environment benign protocol. Also it gives a good outcome in terms of yield and requires a shorter reaction time.

Keywords: Chromene, pyridine, multicomponent reaction, microwave irradiation.

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