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Current Drug Targets


ISSN (Print): 1389-4501
ISSN (Online): 1873-5592

Review Article

Anti-VEGF and Retinal Dystrophies

Author(s): Maurizio Battaglia Parodi, Pierluigi Iacono* and Stefano Da Pozzo

Volume 21 , Issue 12 , 2020

Page: [1201 - 1207] Pages: 7

DOI: 10.2174/1389450121666200428103334

Price: $65


The therapeutic approach based on anti-vascular endothelial growth factor (anti-VEGF) molecules can be used to treat two important complications of retinal dystrophies: choroidal neovascularization and macular edema. The macular involvement in retinal dystrophies can lead to further visual deterioration in patients at a young age and already affected by functional limitations. The study reports the effect of anti-VEGF treatment in several subforms of retinal dystrophies, critically discussing advantages and limitations.

Keywords: Choroidal neovascularization, macular edema retinitis pigmentosa, best vitelliform macular dystrophy, stargardt disease, pattern dystrophy, anti-VEGF.

Graphical Abstract
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