摘要
认识到肠道菌群在健康和疾病进展中的重要作用,调节其组成以及与生物体的新陈代谢的尝试已引起特别关注。 大量研究表明,肠道菌群功能失调或失衡与疾病进展密切相关,包括内分泌疾病,神经退行性疾病,肿瘤,心血管疾病等。数百年来,草药已在全球范围内用于预防和治疗疾病。 尽管潜在的机制似乎很复杂,但是重要的机制之一是通过调节肠道菌群。 在这篇综述中,最新发表的论文总结了草药与微生物群之间的共代谢以及潜在的途径。
关键词: 中草药,肠道菌群,新陈代谢,机制,功能障碍,失衡。
Current Drug Targets
Title:Pivotal Role of the Interaction Between Herbal Medicines and Gut Microbiota on Disease Treatment
Volume: 22 Issue: 3
关键词: 中草药,肠道菌群,新陈代谢,机制,功能障碍,失衡。
摘要: With the recognition of the important role of gut microbiota in both health and disease progression, attempts to modulate its composition, as well as its co-metabolism with the organism, have attracted special attention. Abundant studies have demonstrated that dysfunction or imbalance of gut microbiota is closely related to disease progression, including endocrine diseases, neurodegenerative diseases, tumors, cardiovascular diseases, etc. Herbal medicines have been applied to prevent and treat diseases worldwide for hundreds of years. Although the underlying mechanism seems to be complex, one of the important ones is through modulating gut microbiota. In this review, co-metabolism between herbal medicines and microbiota, as well as the potential pathways are summarized from most recent published papers.
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Pivotal Role of the Interaction Between Herbal Medicines and Gut Microbiota on Disease Treatment, Current Drug Targets 2021; 22 (3) . https://dx.doi.org/10.2174/1389450121666200324151530
DOI https://dx.doi.org/10.2174/1389450121666200324151530 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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