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Current Pharmaceutical Design


ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Review Article

Natural Antioxidants, Health Effects and Bioactive Properties of Wild Allium Species

Author(s): Spyridon A. Petropoulos*, Francesco Di Gioia, Nikos Polyzos and Nikos Tzortzakis

Volume 26, Issue 16, 2020

Page: [1816 - 1837] Pages: 22

DOI: 10.2174/1381612826666200203145851

Price: $65


Background: There is an increasing interest from the pharmaceutical and food industry in natural antioxidant and bioactive compounds derived from plants as substitutes for synthetic compounds. The genus Allium is one of the largest genera, with more than 900 species, including important cultivated and wild species, having beneficial health effects.

Objective: The present review aims to unravel the chemical composition of wild Allium species and their healthrelated effects, focusing on the main antioxidant compounds. For this purpose, a thorough study of the literature was carried out to compile reports related to health effects and the principal bioactive compounds. Considering the vast number of species, this review is divided into subsections where the most studied species are presented, namely Allium ampeloprasum, A. flavum, A. hookeri, A. jesdianum, A. neapolitanum, A. roseum, A. stipitatum, A. tricoccum, and A. ursinum, with an additional composite section for less studied species.

Methods: The information presented in this review was obtained from worldwide accepted databases such as Scopus, ScienceDirect, PubMed, Google Scholar and Researchgate, using as keywords the respective names of the studied species (both common and Latin names) and the additional terms of “antioxidants” “health effects” and “bioactive properties”.

Conclusion: The genus Allium includes several wild species, many of which are commonly used in traditional and folklore medicine while others are lesser known or are of regional interest. These species can be used as sources of natural bioactive compounds with remarkable health benefits. Several studies have reported these effects and confirmed the mechanisms of action in several cases, although more research is needed in this field. Moreover, considering that most of the studies refer to the results obtained from species collected in the wild under uncontrolled conditions, further research is needed to elucidate the effects of growing conditions on bioactive compounds and to promote the exploitation of this invaluable genetic material.

Keywords: Alliaceae, health effects, natural antioxidants, organosulfur compounds, saponins, wild species.

O’Donnell G, Poeschl R, Zimhony O, et al. Bioactive pyridine-N-oxide disulfides from Allium stipitatum. J Nat Prod 2009; 72(3): 360-5.
[] [PMID: 19093848]
Jabrane A, Ben Jannet H, Miyamoto T, et al. Spirostane and cholestane glycosides from the bulbs of Allium nigrum L. Food Chem 2011; 125(2): 447-55.
[] [PMID: 23140685]
García-Herrera P, Morales P, Fernández-Ruiz V, et al. Nutrients, phytochemicals and antioxidant activity in wild populations of Allium ampeloprasum L., a valuable underutilized vegetable. Food Res Int 2014; 62: 272-9.
Dey P, Khaled KL. An Extensive review on Allium ampeloprasum a magical herb. Int J Sci Res (Ahmedabad) 2015; 4(7): 371-7.
Santas J, Almajano MP, Carbó R. Antimicrobial and antioxidant activity of crude onion (Allium cepa, L.) extracts. Int J Food Sci Technol 2010; 45(2): 403-9.
Petropoulos S, Fernandes Â, Barros L, Ciric A, Sokovic M, Ferreira ICFR. Antimicrobial and antioxidant properties of various Greek garlic genotypes. Food Chem 2018; 245: 7-12.
[] [PMID: 29287429]
Martins N, Petropoulos S, Ferreira ICFR. Chemical composition and bioactive compounds of garlic (Allium sativum L.) as affected by pre- and post-harvest conditions: A review. Food Chem 2016; 211: 41-50.
[] [PMID: 27283605]
Sarić-Kundalić B, Dobeš C, Klatte-Asselmeyer V, Saukel J. Ethnobotanical study on medicinal use of wild and cultivated plants in middle, south and west Bosnia and Herzegovina. J Ethnopharmacol 2010; 131(1): 33-55.
[] [PMID: 20594943]
Petropoulos S, Di Gioia F, Ntatsi G. Vegetable organosulfur compounds and their health promoting effects. Curr Pharm Des 2017; 23(19): 2850-75.
[] [PMID: 28078991]
Mamedov N, Gardner Z, Craker LE. Medicinal plants used in russia and central Asia for the treatment of selected skin conditions. J Herbs Spices Med Plants 2005; 11(2): 191-222.
Schmidt JS, Nyberg NT, Staerk D. Assessment of constituents in Allium by multivariate data analysis, high-resolution α-glucosidase inhibition assay and HPLC-SPE-NMR. Food Chem 2014; 161: 192-8.
[] [PMID: 24837940]
Štajner D, Milić N, Canadanović-Brunet J. An investigation into the antioxidant activity of Allium nutans L. Phytother Res 1999; 13(4): 333-6.
[<333:AID-PTR450>3.0.CO;2-Y] [PMID: 10404542]
Štajner D, Milić-Demarino N, Canadanović-Brunet J, Štajner M, Popović BM. Screening for antioxidant properties of Allium giganteum. Fitoterapia 2006; 77(4): 268-70.
[] [PMID: 16690227]
Tarakci Z, Temiz H. A review of the chemical, biochemical and antimicrobial aspects of Turkish Otlu (herby) cheese. Int J Dairy Technol 2009; 62(3): 354-60.
Tarakci Z, Temiz H, Aykut U, Turhan S. Influence of wild garlic on color, free fatty acids, and chemical and sensory properties of herby pickled cheese. Int J Food Prop 2011; 14(2): 287-99.
Farzan B, Abbaszadeh S, Teimouri H. Ethnobotanical treatments for earache and sore throat. Int J Res Pharm Sci 2019; 10(2): 1354-60.
Au DT, Wu J, Jiang Z, Chen H, Lu G, Zhao Z. Ethnobotanical study of medicinal plants used by Hakka in Guangdong, China. J Ethnopharmacol 2008; 117(1): 41-50.
[] [PMID: 18313871]
Khojimatov OK, Abdiniyazova GJ, Pak VV. Some wild growing plants in traditional foods of Uzbekistan. J Ethn Foods 2015; 2(1): 25-8.
Keusgen M, Fritsch RM, Hisoriev H, Kurbonova PA, Khassanov FO. Wild Allium species (Alliaceae) used in folk medicine of Tajikistan and Uzbekistan. J Ethnobiol Ethnomed 2006; 2: 18.
[] [PMID: 16584547]
Parsaei P, Bahmani M, Naghdi N, Asadi-Samani M, Rafieian-Kopaei MM, Boroujeni S. Shigellosis phytotherapy: A review of the most important native medicinal plants. Der Pharm Lett 2016; 8(2): 249-55.
Beigh SY, Nawchoo IA, Iqbal M. Traditional veterinary medicine among the tribes of kashmir himalaya. J Herbs Spices Med Plants 2003; 10(4): 121-7.
Etxeberria U, de la Garza AL, Campión J, Martínez JA, Milagro FI. Antidiabetic effects of natural plant extracts via inhibition of carbohydrate hydrolysis enzymes with emphasis on pancreatic alpha amylase. Expert Opin Ther Targets 2012; 16(3): 269-97.
[] [PMID: 22360606]
Pieroni A, Dibra B, Grishaj G, Grishaj I, Gjon Maçai S. Traditional phytotherapy of the Albanians of Lepushe, Northern Albanian Alps. Fitoterapia 2005; 76(3-4): 379-99.
[] [PMID: 15890470]
Block E, Naganathan S, Putman D, Zhao SH. Allium chemistry: hplc analysis of thiosulfinates from onion, garlic, wild garlic (ramsoms), leek, scallion, shallot, elephant (great-headed) garlic, chive, and Chinese chive. Uniquely high allyl to methyl ratios in some garlic samples. J Agric Food Chem 1992; 40(12): 2418-30.
Block E, Naganathan S, Putman D, Zhao SH. Organosulfur chemistry of garlic and onion: Recent results. Pure Appl Chem 1993; 65(4): 625-32.
Iranshahi M. A review of volatile sulfur-containing compounds from terrestrial plants: biosynthesis, distribution and analytical methods. J Essent Oil Res 2012; 24(4): 393-434.
Kyung KH. Antimicrobial properties of allium species. Curr Opin Biotechnol 2012; 23(2): 142-7.
[] [PMID: 21903379]
Arnault I, Auger J. Seleno-compounds in garlic and onion. J Chromatogr A 2006; 1112(1-2): 23-30.
[] [PMID: 16480995]
Baser KHC, Kosar M, Koyuncu M. Composition of the essential oil of Allium macrochaetum Boiss. et Hausskn. from Turkey. J Essent Oil Res 1997; 9(1): 125-6.
Boscher J, Auger J, Mandon N, Ferary S. Qualitative and quantitative comparison of volatile sulphides and flavour precursors in different organs of some wild and cultivated garlics. Biochem Syst Ecol 1995; 23(7–8): 787-91.
Kusterer J, Keusgen M. Cysteine sulfoxides and volatile sulfur compounds from Allium tripedale. J Agric Food Chem 2010; 58(2): 1129-37.
[] [PMID: 20030404]
Kubec R, Kim S, McKeon DM, Musah RA. Isolation of S-n-butylcysteine sulfoxide and six n-butyl-containing thiosulfinates from Allium siculum. J Nat Prod 2002; 65(7): 960-4.
[] [PMID: 12141853]
Ramirez DA, Locatelli DA, González RE, Cavagnaro PF, Camargo AB. Analytical methods for bioactive sulfur compounds in Allium: An integrated review and future directions. J Food Compos Anal 2017; 61: 4-19.
Storsberg J, Schulz H, Keller ERJ. Chemotaxonomic Classification of some Allium wild species on the basis of their volatile sulphur compounds. J Appl Bot 2003; 77(5–6): 160-2.
Storsberg J, Schulz H, Keusgen M, Tannous F, Dehmer KJ, Keller ERJ. Chemical characterization of interspecific hybrids between Allium cepa L. and Allium kermesinum Rchb. J Agric Food Chem 2004; 52(17): 5499-505.
[] [PMID: 15315391]
Sparg SG, Light ME, van Staden J. Biological activities and distribution of plant saponins. J Ethnopharmacol 2004; 94(2-3): 219-43.
[] [PMID: 15325725]
Cyboran-Mikolajczyk S, Kleszczynska H, Oszmianski J, Paslawski R. Allium ursinum L. leaves components modified the physico-chemical properties of red blood cells protecting them from the effects of oxidative stress. Acta Pol Pharm -. Drug Res (Stuttg) 2019; 76(3): 483-91.
Khazaei S, Abdul Hamid R, Mohd Esa N, et al. Promotion of HepG2 cell apoptosis by flower of Allium atroviolaceum and the mechanism of action. BMC Complement Altern Med 2017; 17(1): 104.
[] [PMID: 28187719]
Mimaki Y, Kawashima K, Kanmoto T, Sashida Y. Steroidal glycosides from Allium albopilosum and A. ostrowskianum. Phytochemistry 1993; 34(3): 799-805.
[] [PMID: 7764153]
Upadhyay SK, Saurabh S, Singh R, et al. Purification and characterization of a lectin with high hemagglutination property isolated from Allium altaicum. Protein J 2011; 30(6): 374-83.
[] [PMID: 21732172]
Di Gioia F, Petropoulos SA. Phytoestrogens, phytosteroids and saponins in vegetables: Biosynthesis, functions, health effects and practical applications Advances in Food and Nutrition Research. 1.351-421 Elsevier Inc 2019; 90: 351-421.
Petropoulos SA, Fernandes Â, Ntatsi G, Petrotos K, Barros L, Ferreira ICFR. Nutritional value, chemical characterization and bulb morphology of Greek Garlic landraces. Molecules 2018; 23(2): 1-14.
[] [PMID: 29393882]
Lanzotti V. Bioactive saponins from Allium and Aster Plants. Phytochem Rev 2005; 4(2–3): 95-110.
Maisashvili MR, Kuchukhidze DK, Kikoladze VS, Gvazava LN. Steroidal glycosides of gitogenin from Allium rotundum. Chem Nat Compd 2012; 48(1): 86-90.
Kawashima K, Mimaki Y, Sashida Y. Steroidal saponins from the bulbs of Allium schubertii. Phytochemistry 1993; 32(5): 1267-72.
[] [PMID: 7763477]
Kawashima K, Mimaki Y, Sashida Y. Steroidal saponins from Allium giganteum and A. aflatunense. Phytochemistry 1991; 30(9): 3063-7.
Mimaki Y, Nikaido T, Matsumoto K, Sashida Y, Ohmoto T. New steroidal saponins from the bulbs of Allium giganteum exhibiting potent inhibition of cAMP phosphodiesterase activity. Chem Pharm Bull (Tokyo) 1994; 42(3): 710-4.
[] [PMID: 8004721]
Kawashima K, Mimaki Y, Sashida Y, Schubertosides AD. new (22s)-hydroxycholestane glycosides from Allium schubertii. Chem Pharm Bull (Tokyo) 1991; 39(10): S1878522016300157
Zolfaghari B, Barile E, Capasso R, Izzo AA, Sajjadi SE, Lanzotti V. The sapogenin atroviolacegenin and its diglycoside atroviolaceoside from Allium atroviolaceum. J Nat Prod 2006; 69(2): 191-5.
[] [PMID: 16499315]
Fossen T, Andersen ØM, Øvstedal DO, Pedersen AT, Raknes Å. Characteristic anthocyanin pattern from onions and other Allium spp. J Food Sci 1996; 61(4): 703-6.
Sahnoun D, Ksouri WM, Younes I, et al. Antioxidant activity and biochemical composition of fresh bulbs and leaves of wild garlic Allium ursinum. J Nat Sci 2017; 44(2): 2392-9.
Rietz B, Isensee H, Strobach H, Makdessi S, Jacob R. Cardioprotective actions of wild garlic (allium ursinum) in ischemia and reperfusion. Mol Cell Biochem 1993; 119(1-2): 143-50.
[] [PMID: 8455576]
Onduka T, Mochida K, Harino H, Ito K, Kakuno A, Fujii K. Toxicity of metal pyrithione photodegradation products to marine organisms with indirect evidence for their presence in seawater. Arch Environ Contam Toxicol 2010; 58(4): 991-7.
[] [PMID: 19967345]
Möller M, Adam W, Saha-Möller CR, Stopper H. Studies on cytotoxic and genotoxic effects of N-hydroxypyridine-2-thione (Omadine) in L5178Y mouse lymphoma cells. Toxicol Lett 2002; 136(1): 77-84.
[] [PMID: 12368059]
Egebjerg MM, Olesen PT, Eriksen FD, Ravn-Haren G, Bredsdorff L, Pilegaard K. Are wild and cultivated flowers served in restaurants or sold by local producers in Denmark safe for the consumer? Food Chem Toxicol 2018; 120(June): 129-42.
[] [PMID: 29981787]
Mskhiladze L, Legault J, Lavoie S, et al. Cytotoxic steroidal saponins from the flowers of Allium leucanthum. Molecules 2008; 13(12): 2925-34.
[] [PMID: 19037184]
Hirschegger P, Jakše J, Trontelj P, Bohanec B. Origins of Allium ampeloprasum horticultural groups and a molecular phylogeny of the section Allium (Allium: Alliaceae). Mol Phylogenet Evol 2010; 54(2): 488-97.
[] [PMID: 19733249]
Brewster JL. Onions and othe vegetable Alliums, 2nd Edition N. 2nd ed. Wallingford: CABI 2008.
Nguyen NH, Driscoll HE, Specht CD. A molecular phylogeny of the wild onions (Allium; Alliaceae) with a focus on the western North American center of diversity. Mol Phylogenet Evol 2008; 47(3): 1157-72.
[] [PMID: 18226928]
Samaha AA, Fawaz M, Salami A, Baydoun S, Eid AH. Antihypertensive Indigenous lebanese plants: ethnopharmacology and a clinical trial. Biomolecules 2019; 9(292): 1-16.
[] [PMID: 31330767]
Romojaro A, Botella MÁ, Obón C, Pretel MT. Nutritional and antioxidant properties of wild edible plants and their use as potential ingredients in the modern diet. Int J Food Sci Nutr 2013; 64(8): 944-52.
[] [PMID: 23944868]
Adawia K, Rawaa AK, Ghalia S. Phytochemical screening and antioxidant activity of selected wild plants in Liliaceae family growing Syria. Int J Pharmacogn Phytochem Res 2016; 8(12): 2025-32.
Maidment DCJ, Dembny Z, Watts DI. 2001.The antibacterial activity of 12 Allium against Escherichia coli. Nutr Food Sci 2001; 31(5): 238-41.
Nickavar B, Yousefian N. Inhibitory effects of six Allium species on α-amylase enzyme activity. Iran J Pharm Res 2009; 8(1): 53-7.
Mosavat SH, Ghahramani L, Sobhani Z, Haghighi ER, Chaijan MR, Heydari M. The effect of leek (Allium iranicum (Wendelbo)) leaves extract cream on hemorrhoid patients: A double blind randomized controlled clinical trial. Eur J Integr Med 2015; 7(6): 669-73.
Fritsch RM, Keusgen M. Occurrence and taxonomic significance of cysteine sulphoxides in the genus Allium L. (Alliaceae). Phytochemistry 2006; 67(11): 1127-35.
[] [PMID: 16626766]
Sadeghi M, Zolfaghari B, Senatore M, Lanzotti V. Antifungal cinnamic acid derivatives from Persian leek (Allium ampeloprasum Subsp. Persicum). Phytochem Lett 2013; 6(3): 360-3.
Sata N, Matsunaga S, Fusetani N, Nishikawa H, Takamura S, Saito T. New antifungal and cytotoxic steroidal saponins from the bulbs of an elephant garlic mutant. Biosci Biotechnol Biochem 1998; 62(10): 1904-11.
[] [PMID: 9836426]
Simin N, Orcic D, Cetojevic-Simin D, et al. Phenolic profile, antioxidant, anti-inflammatory and cytotoxic activities of small yellow onion (Allium flavum L. subsp. flavum, Alliaceae). Lebensm Wiss Technol 2013; 54(1): 139-46.
Štajner D, Popović BM. Comparative study of antioxidant capacity in organs of different Allium species. Cent Eur J Biol 2009; 4(2): 224-8.
Mitić-Ćulafić D, Nikolić B, Simin N, et al. Effect of Allium flavum L. and Allium melanantherum Panč. Extracts on oxidative DNA damage and antioxidative enzymes superoxide dismutase and catalase. Plant Foods Hum Nutr 2016; 71(1): 28-34.
[] [PMID: 26590605]
Stajner D, Szöllosi Varga I. An evaluation of the antioxidant abilities of Allium species. Acta Biol Szeged 2003; 47(1-4): 103-6.
Aleksandar P, Dragana MĆ, Nebojša J, et al. Wild edible onions - Allium flavum and Allium carinatum - successfully prevent adverse effects of chemotherapeutic drug doxorubicin. Biomed Pharmacother 2019; 109(109): 2482-91.
[] [PMID: 30551509]
Rezgui A, Mitaine-Offer AC, Paululat T, Delemasure S, Dutartre P, Lacaille-Dubois MA. Cytotoxic steroidal glycosides from Allium flavum. Fitoterapia 2014; 93: 121-5.
[] [PMID: 24380693]
Sobolewska D, Michalska K, Podolak I, Grabowska K. Steroidal saponins from the genus Allium. Phytochem Rev 2016; 15(1): 1-35.
[] [PMID: 26893594]
Curcic MG, Stankovic MS, Radojevic ID, et al. Biological effects, total phenolic content and flavonoid concentrations of fragrant yellow onion (Allium flavum L.). Med Chem 2012; 8(1): 46-51.
[] [PMID: 22420550]
Milutinović M, Stanković M, Cvetković D, Maksimović V, Šmit B, Pavlović R, et al. The molecular mechanisms of apoptosis induced by Allium flavum L. and Synergistic effects with new-synthesized pd(ii) complex on colon cancer cells. J Food Biochem 2015; 39(3): 238-50.
Bok SH, Seo JH, Bae CS, Kang B, Cho SS, Park DH. Allium hookeri root extract regulates asthmatic changes through immunological modulation of Th1/Th2‑related factors in an ovalbumin‑induced asthma mouse model. Mol Med Rep 2019; 20(4): 3215-23.
[] [PMID: 31432168]
Kima JE, Seo J-H, Bae M-S, et al. Antimicrobial constituents from Allium hookeri root. Nat Prod Commun 2016; 11(2): 237-8.
[PMID: 27032210]
Jun H. Isolation and characterization of phenolic compound from Allium hookeri root for potential use as antioxidant in foods. Food Sci Biotechnol 2015; 24(6): 2031-4.
Kim S, Kim DB, Lee S, Park J, Shin D, Yoo M. Profiling of organosulphur compounds using HPLC-PDA and GC/MS system and antioxidant activities in hooker chive (Allium hookeri). Nat Prod Res 2016; 30(24): 2798-804.
[] [PMID: 27054954]
Rhyu DY, Park SH. Characterization of alkyl thiosulfinate in Allium hookeri root using HPLC-ESI-MS. J Korean Soc Appl Biol Chem 2013; 56(4): 457-9.
Yang HS, Choi YJ, Jin HY, Lee SC, Huh CK. Effects of Allium hookeri root water extracts on inhibition of adipogenesis and GLUT-4 expression in 3T3-L1 adipocytes. Food Sci Biotechnol 2016; 25(2): 615-21.
[] [PMID: 30263314]
Roh SS, Kwon OJ, Yang JH, et al. Allium hookeri root protects oxidative stress-induced inflammatory responses and β-cell damage in pancreas of streptozotocin-induced diabetic rats. BMC Complement Altern Med 2016; 16(63): 63.
[] [PMID: 26888412]
Yang MH, Kim NH, Heo JD, et al. Comparative evaluation of sulfur compounds contents and antiobesity properties of allium hookeri prepared by different drying methods. Evidence-Based Complement Altern Med 2017. 1-10. 2436927.
Nan L, Nam HH, Choo BK, et al. An ethanolic extract of Allium hookeri root alleviates reflux esophagitis and modulates NF-κB Signaling. Evidence-Based Complement Altern Med. 2018. 1-8.1834681.
Park H, Jeong J, Hyun H. Kim J, Kim H, Oh H. Effects of a hot-water extract of Allium hookeri roots on bone formation in human osteoblast-like MG-63 cells in vitro and in rats in vivo. Planta Med 2016; 82(16): 1410-5.
Park S, No K, Lee J. Anti-obesity effect of allium hookeri leaf extract in high-fat diet-fed mice. J Med Food 2018; 21(3): 254-60.
[] [PMID: 29315003]
Park SY, Je JY, Ahn CB. Phenolic composition and hepatoprotective activities of Allium hookeri against hydrogen-peroxide-induced oxidative stress in cultured hepatocytes. J Food Biochem 2016; 40(3): 284-93.
Lee Y, Lee SH, Jeong MS, et al. In vitro analysis of the immunomodulating effects of Allium hookeri on lymphocytes, macrophages, and tumour cells. J Poult Sci 2017; 54(2): 142-8.
Jang JY, Lee MJ, You BR, et al. Allium hookeri root extract exerts anti-inflammatory effects by nuclear factor-KB down-regulation in lipopolysaccharide-induced RAW264.7 cells. BMC Complement Altern Med 2017; 17(1): 1-9.
[PMID: 28049463]
Jeong HJ, Yoou MS, Han NR, Hwang SY, Yoon KW, Kim HM. The new therapeutic herbal drug HM0601 and its bioactive compound rutin exert potent antiproliferative activities in mast cells. Fundam Clin Pharmacol 2018; 32(3): 279-87.
[] [PMID: 29368407]
Kim H-Y, Nam S-Y, Hong S-W, Kim M-J, Jeong H-J, Kim H-M. Protective effects of rutin through regulation of vascular endothelial growth factor in allergic rhinitis. Am J Rhinol Allergy 2015; 29(3): e87-94.
[] [PMID: 25975244]
Kim HY, Rho SH, Lim JH, Park HJ, Jeong HJ. Protective effect of linoleic acid against inflammatory reactions by mast cell via caspase-1 cascade pathways. J Food Biochem 2019; 43(8) e12932
[] [PMID: 31368553]
Kim JE, Park KM, Lee SY, et al. Anti-inflammatory effect of Allium hookeri on carrageenan-induced air pouch mouse model. PLoS One 2017; 12(12) e0190305
[] [PMID: 29281705]
Jung HY, Lee KY, Yoo DY, et al. Essential oils from two Allium species exert effects on cell proliferation and neuroblast differentiation in the mouse dentate gyrus by modulating brain-derived neurotrophic factor and acetylcholinesterase. BMC Complement Altern Med 2016; 16(1): 431.
[] [PMID: 27809818]
Li R, Wang Y-F, Sun Q, Hu H-B. Chemical composition and antimicrobial activity of the essential oil from Allium hookeri consumed in Xishuangbanna, southwest China. Nat Prod Commun 2014; 9(6): 863-4.
[] [PMID: 25115101]
Rafieian-Kopaei M, Bahmani M, Sepahvand A, et al. Candidiasis phytotherapy: An overview of the most important medicinal plants affecting the Candida albicans. J Chem Pharm Sci 2016; 9(3): 1255-62.
Lanzotti V, Scala F, Bonanomi G. Compounds from Allium species with cytotoxic and antimicrobial activity. Phytochem Rev 2014; 13(4): 769-91.
Mimaki Y, Kuroda M, Fukasawa T, Sashida Y. Steroidal glycosides from the bulbs of Allium jesdianum. J Nat Prod 1999; 62(1): 194-7.
[] [PMID: 9917320]
Kalantari H, Keshavarzi E, Kheradmand P, Goodarzian M, Zeidooni L. Protective effect hydroalcoholic extract Allium jesdianum Boiss against CCl4-induced hepatotoxicity in Male mice. J Reports Pharm Sci 2018; 7(3): 389-99.
Kalantari H, Ehsan TS, Samimi A, Kheradmand P, Shirani M, Zeidooni L. Histopathological and biomedical parameters determination in the protective effect of hydroalcoholic extract of Allium jesdianum on hepatotoxicity induced by bromobenzene. Iran J Pharm Sci 2018; 14(2): 15-24.
Kalantari H, Pajou MD, Kheradmand P, Goodarzian M, Zeidooni L. Nephroprotective effect of hydroalcoholic extract Allium jesdianum Boiss against carbon tetrachloride induced nephrotoxicity via stress oxidative in mice. Pharm Sci 2018; 24(2): 89-96.
Pirbalouti AG. Phytochemical and bioactivity diversity in the extracts from bulbs and leaves of different populations of Allium jesdianum, a valuable underutilized vegetable. Acta Sci Pol Hortorum Cultus 2019; 18(2): 115-22.
Vahdani R, Mehrabi S, Malekzadeh J, Sadeghi H, Jannesar R, Mehrabi F. Effects of hydrophilic extract of Allium jesdianum on prevention and treatment of ethylene glycol induced renal stone in male wistar rats. Life Sci J 10(12): 17-21.
D’Antuono LF, Manco MA. Preliminary sensory evaluation of edible flowers from wild Allium species. J Sci Food Agric 2013; 93(14): 3520-3.
[] [PMID: 23821357]
Carotenuto A, Fattorusso E, Lanzotti V, Magno S, De Feo V, Cicala C. The flavonoids of Allium neapolitanum. Phytochemistry 1997; 44(5): 949-57.
[] [PMID: 9115694]
Nencini C, Franchi GG, Micheli L. Cardiovascular receptor binding affinity of aqueous extracts from Allium species. Int J Food Sci Nutr 2010; 61(4): 433-9.
[] [PMID: 20446820]
Nencini C, Franchi GG, Cavallo F, Micheli L. Protective effect of Allium neapolitanum Cyr. versus Allium sativum L. on acute ethanol-induced oxidative stress in rat liver. J Med Food 2010; 13(2): 329-35.
[] [PMID: 20192846]
Nencini C, Menchiari A, Franchi GG, Micheli L. In vitro antioxidant activity of aged extracts of some Italian Allium species. Plant Foods Hum Nutr 2011; 66(1): 11-6.
[] [PMID: 21290188]
Diǧrak M, Hakki Alma M, Ilçim A. Antibacterial and antifungal activities of Turkish medicinal plants. Pharm Biol 2001; 39(5): 346-50.
O’Donnell G, Gibbons S. 2008. Antibacterial activity of two canthin-6-one alkaloids from Allium neapolitanum. Phytother Res 2007; 21(7): 653-7. 117934759/abstract
Casiglia S, Bruno M, Senatore F. Composition of the essential oil of allium neapolitanum cirillo growing wild in sicily and its activity on microorganisms affecting historical art crafts. J Oleo Sci 2015; 64(12): 1315-20.
[] [PMID: 26632947]
Ranfa A, Bodesmo M. An ethnobotanical investigation of traditional knowledge and uses of edible wild plants in the Umbria Region, Central Italy. J Appl Bot Food Qual 2017; 90: 246-58.
Najjaa H, Zerria K, Fattouch S, Ammar E, Neffati M. Antioxidant and antimicrobial activities of Allium roseum L. “Lazoul,” a wild edible endemic species in North Africa. Int J Food Prop 2011; 14(2): 371-80.
Najjaa H, Boubakri A, Ben Arfa A, Zouari N, Neffati M. Salinity and drought stresses improve antioxidant potential of Allium roseum L., an edible medicinal plant. Acta Physiol Plant 2018; 40(11): 1-7.
Imen A, Najjaa H, Neffati M. Influence of sulfur fertilization on S-containing, phenolic, and carbohydrate metabolites in rosy garlic (Allium roseum L.): A wild edible species in North Africa. Eur Food Res Technol 2013; 237(4): 521-7.
Zouari S, Ketata M, Boudhrioua N, Ammar E. Allium roseum L. volatile compounds profile and antioxydant activity for chemotype discrimination - Case study of the wild plant of Sfax (Tunisia). Ind Crops Prod 2013; 41(1): 172-8.
Zouari S, Najjaa H, Neffati M, Ammar E. A new essential oil chemotype of Allium roseum analyzed by an apolar column. Int J Food Prop 2012; 15(2): 385-97.
Snoussi M, Trabelsi N, Dehmeni A, et al. Phytochemical analysis, antimicrobial and antioxidant activities of Allium roseum var. odoratissimum (Desf.) Coss extracts. Ind Crops Prod 2016; 89: 533-42.
Najjaa H, Zouari S, Ammar E, Neffati M. Phytochemical screening and antibacterial properties of Allium roseum L., a wild edible species in north Africa. J Food Biochem 2011; 35(3): 699-714.
Omoloso AD, Vagi JK. Broad spectrum antibacterial activity of Allium cepa, Allium roseum, Trigonella foenum graecum and Curcuma domestica. Nat Prod Sci 2001; 7(1): 13-6.
Dziri S, Hassen I, Fatnassi S, et al. Phenolic constituents, antioxidant and antimicrobial activities of rosy garlic (Allium roseum var. odoratissimum). J Funct Foods 2012; 4(2): 423-32.
Rouis-Soussi SL, Boughelleb-M’Hamdi N, El Ayeb-Zakhama A, Flamini G, Ben Jannet H, Harzallah-Skhiri F. Phytochemicals, antioxidant and antifungal activities of Allium roseum var. grandiflorum subvar. typicum Regel. S Afr J Bot 2014; 91: 63-70.
Hichem B jannet, Lamia SR, Mohamed N, Zine M. Chemical composition of flowers and stems essential oils from the Tunisian Allium roseum L. J Essent Oil-Bearing Plants 2007; 10(2): 151-6.
Najjaa H, Neffati M, Zouari S, Ammar E. Essential oil composition and antibacterial activity of different extracts of Allium roseum L., a North African endemic species. C R Chim 2007; 10(9): 820-6.
Touihri I, Boukhris M, Marrakchi N, Luis J, Hanchi B, Kallech-Ziri O. Chemical composition and biological activities of Allium roseum L. var. grandiflorum Briq. essential oil. J Oleo Sci 2015; 64(8): 869-79.
[] [PMID: 26179004]
Souid S, Najjaa H, Riahi-Chebbi I, et al. Allium roseum L. extract exerts potent suppressive activities on chronic myeloid leukemia K562 cell viability through the inhibition of BCR-ABL, PI3K/Akt, and ERK1/2 pathways and the abrogation of vegf secretion. Nutr Cancer 2017; 69(1): 117-30.
[] [PMID: 27892697]
Pirbalouti AG, Ahmadzadeh Y, Malekpoor F. Variation in antioxidant, and antibacterial activities and total phenolic content of the bulbs of mooseer (Allium hirtifolium Boiss.). Acta Agric Slov 2015; 105(1): 15-22.
Lanzotti V. Bioactive polar natural compounds from garlic and onions. Phytochem Rev 2012; 11(2–3): 179-96.
Krejčová P, Kučerová P, Stafford GI, Jäger AK, Kubec R. Antiinflammatory and neurological activity of pyrithione and related sulfur-containing pyridine N-oxides from Persian shallot (Allium stipitatum). J Ethnopharmacol 2014; 154(1): 176-82.
[] [PMID: 24721027]
Kubec R, Krejcová P, Šimek P, Václavík L, Hajslová J, Schraml J. Precursors and formation of pyrithione and other pyridyl-containing sulfur compounds in drumstick onion, Allium stipitatum. J Agric Food Chem 2011; 59(10): 5763-70.
[] [PMID: 21510712]
Karunanidhi A, Ghaznavi-Rad E, Jeevajothi Nathan J, et al. Bioactive 2-(methyldithio)pyridine-3-carbonitrile from Persian shallot (Allium stipitatum Regel.) exerts broad-spectrum antimicrobial activity. Molecules 2019; 24(6): 1-12.
[] [PMID: 30871159]
Danquah CA, Kakagianni E, Khondkar P, et al. Analogues of disulfides from Allium stipitatum demonstrate potent anti-tubercular activities through drug efflux pump and biofilm inhibition. Sci Rep 2018; 8(1): 1150.
[] [PMID: 29348586]
Karunanidhi A, Ghaznavi-Rad E, Hamat RA, et al. Antibacterial and antibiofilm activities of nonpolar extracts of allium stipitatum regel. against multidrug resistant bacteria. BioMed Res Int 2018; 2018 9845075
[] [PMID: 30105271]
Elahe AD, Mahmoud RK, Abdollah GP, Bahmani M. The antibacterial effects of wild and cultivated Allium hirtifolium Boiss on Pseudomonas aeruginosa and Enterococcus faecalis and antibiotic resistance patterns of the strains using disk diffusion. J Chem Pharm Sci 2016; 9(4): 3409-13.
Karunanidhi A, Ghaznavi-Rad E, Nathan JJ, et al. Antifungal and antibiofilm activity of Persian shallot (Allium stipitatum Regel.) against clinically significant Candida spp. Trop Biomed 2018; 35(3): 815-25.
Karunanidhi A, Ghaznavi-Rad E, Nathan JJ, Abba Y, Van Belkum A, Neela V. Allium stipitatum extract exhibits in vivo antibacterial activity against methicillin-resistant Staphylococcus aureus and accelerates burn wound healing in a full-thickness murine burn modelEvidence-Based Complement Altern Med. 2017; 1-13.
Fasihzadeh S, Lorigooini Z, Jivad N. Chemical constituents of Allium stipitatum regel (Persian shallot) essential oil. Der Pharm Lett 2016; 8(1): 175-80.
Jones AG. A study of wild leek, and the recognition of Allium burdickii (Liliaceae). Syst Bot 1979; 4(1): 29-43.
Vasseur L, Gagnon D, Simon JP. Isoenzymatic variability among populations and varieties of wild leek (Allium tricoccum). Biochem Syst Ecol 1990; 18(5): 321-4.
Chamberlain J, Small C, Baumflek M. Sustainability forest management for nontimber products. Sustain 2019; 11(9): 1-21.
Baumflek M, Chamberlain JL. Ramps reporting: What 70 years of popular media tells us about a cultural keystone species. Southeast Geogr 2019; 59(1): 77-96.
Davis JM. Assisting farmers to produce high-quality medicinal herbs. HortScience 2012; 47(8): 976-8.
Dion PP, Bussières J, Lapointe L. Sustainable leaf harvesting and effects of plant density on wild leek cultivation plots and natural stands in Southern Quebec, Canada. Agrofor Syst 2016; 90(6): 979-95.
Nault A, Gagnon D. Ramet demography of Allium tricoccum, a spring ephemeral, perennial forest herb. J Ecol 1993; 81(1): 101-19.
Vasseur L, Gagnon D. Survival and growth of Allium tricoccum Ait. transplants in different habitats. Biol Conserv 1994; 68(2): 107-14.
Bernatchez A, Bussières J, Lapointe L. Testing fertilizer, gypsum, planting season and varieties of wild leek (Allium tricoccum) in forest farming system. Agrofor Syst 2013; 87(5): 977-91.
Ritchey KD, Schumann CM. Response of woodland-planted ramps to surface-applied calcium, planting density, and bulb preparation. HortScience 2005; 40(5): 1516-20.
Dion PP, Bussières J, Lapointe L. Late canopy closure delays senescence and promotes growth of the spring ephemeral wild leek (Allium tricoccum). Botany 2017; 95(5): 457-67.
Hewins CR, Carrino-Kyker SR, Burke DJ. Seasonal variation in mycorrhizal fungi colonizing roots of Allium tricoccum (wild leek) in a mature mixed hardwood forest. Mycorrhiza 2015; 25(6): 469-83.
[] [PMID: 25634800]
Rothstein DE. Spring ephemeral herbs and nitrogen cycling in a northern hardwood forest: an experimental test of the vernal dam hypothesis. Oecologia 2000; 124(3): 446-53.
[] [PMID: 28308784]
Dion PP, Brisson J, Fontaine B, Lapointe L. Light acclimation strategies change from summer green to spring ephemeral as wild-leek plants age. Am J Bot 2016; 103(5): 963-70.
[] [PMID: 27208363]
Bernatchez A, Lapointe L. Cooler temperatures favour growth of wild leek (Allium tricoccum), a deciduous forest spring ephemeral. Botany 2012; 90(11): 1125-32.
Rock JH, Beckage B, Gross LJ. Population recovery following differential harvesting of Allium tricoccum Ait. in the southern Appalachians. Biol Conserv 2004; 116(2): 227-34.
Zak D, Pregitzer KS. Nitrate assimilation by herbaceous ground flora in late successional forests. J Ecol 1988; 76(2): 537-46.
Calvey EM, White KD, Matusik JE, Sha D, Block E. Allium chemistry: identification of organosulfur compounds in ramp (Allium tricoccum) homogenates. Phytochemistry 1998; 49(2): 359-64.
[] [PMID: 9747536]
Calvey EM, Matusik JE, White KD, DeOrazio R, Sha D, Block E. Allium chemistry: supercritical fluid extraction and lc-apci-ms of thiosulfinates and related compounds from homogenates of garlic, onion, and ramp. identification in garlic and ramp and synthesis of 1-propanesulfinothioic acid s-allyl ester. J Agric Food Chem 1997; 45(11): 4406-13.
Krstin S, Sobeh M, Braun MS, Wink M. Tulbaghia violacea and Allium ursinum extracts exhibit anti-parasitic and antimicrobial activities. Molecules 2018; 23: 313.
[] [PMID: 29393867]
Whanger PD, Ip C, Polan CE, Uden PC, Welbaum G. Tumorigenesis, metabolism, speciation, bioavailability, and tissue deposition of selenium in selenium-enriched ramps (Allium tricoccum). J Agric Food Chem 2000; 48(11): 5723-30.
[] [PMID: 11087545]
Dabeek WM, Kovinich N, Walsh C, Ventura Marra M. Characterization and quantification of major flavonol glycosides in ramps (Allium tricoccum). Molecules 2019; 24(18): 3281.
[] [PMID: 31505821]
Radulović NS, Miltojević AB, Stojković MB, Blagojević PD. New volatile sulfur-containing compounds from wild garlic (Allium ursinum L., Liliaceae). Food Res Int 2015; 78: 1-10.
[] [PMID: 28433269]
Sharifi-Rad J, Mnayer D, Tabanelli G, et al. Plants of the genus Allium as antibacterial agents: From tradition to pharmacy. Cell Mol Biol 2016; 62(9): 57-68.
[PMID: 27585263]
Štajner D, Popović BM, Canadanović-Brunet J, Štajner M. Antioxidant and scavenger activities of Allium ursinum. Fitoterapia 2008; 79(4): 303-5.
[] [PMID: 18313233]
Kęsik T, Błażewicz-Woźniak M, Michowska AE. Influence of mulching and nitrogen nutrition on bear garlic (Allium ursinum L.) growth. Acta Sci Pol Hortorum Cultus 2011; 10(3): 221-33.
Djurdjevic L, Dinic A, Pavlovic P, Mitrovic M, Karadzic B, Tesevic V. Allelopathic potential of Allium ursinum L. Biochem Syst Ecol 2004; 32(6): 533-44.
Gîtin L, Dinică R, Neagu C, Dumitrascu L. Sulfur compounds identification and quantification from Allium spp. fresh leaves. Yao Wu Shi Pin Fen Xi 2014; 22(4): 425-30.
[] [PMID: 28911456]
Satyal P, Craft JD, Dosoky NS, Setzer WN. The chemical compositions of the volatile oils of garlic (Allium sativum) and wild garlic (Allium vineale). Foods 2017; 6(8): 63.
[] [PMID: 28783070]
Putnoky S, Caunii A, Butnariu M. Study on the stability and antioxidant effect of the Allium ursinum watery extract. Chem Cent J 2013; 7(1): 21.
[] [PMID: 23369571]
Schmitt B, Schulz H, Storsberg J, Keusgen M. Chemical characterization of Allium ursinum L. depending on harvesting time. J Agric Food Chem 2005; 53(18): 7288-94.
[] [PMID: 16131144]
Sobolewska D, Podolak I, Makowska-Wąs J. Allium ursinum: botanical, phytochemical and pharmacological overview. Phytochem Rev 2015; 14(1): 81-97.
[] [PMID: 25774103]
Marchese A, Barbieri R, Sanches-Silva A, et al. Antifungal and antibacterial activities of allicin: A review. Trends Food Sci Technol 2016; 52: 49-56.
Pârvu M, Pârvu AE, Vlase L, Rosca-Casian O, Pârvu O. Antifungal properties of Allium ursinum L. ethanol extract. J Med Plants Res 2011; 5(10): 2041-6.
Bagiu RV, Vlaicu B, Butnariu M. Chemical composition and in vitro antifungal activity screening of the Allium ursinum L. (Liliaceae). Int J Mol Sci 2012; 13(2): 1426-36.
[] [PMID: 22408399]
Nacsa-Farkas E, Kerekes E, Kerekes EB, et al. Antifungal effect of selected European herbs against Candida albicans and emerging pathogenic non-albicans Candida species. Acta Biol Szeged 2014; 58(1): 61-4.
Sapunjieva T, Alexieva I, Mihaylova D, Popova A. Antimicrobial and antioxidant activity of extracts of Allium ursinum L. J Biosci Biotechnol 2012; 143-5.
Sobolewska D, Janeczko Z, Kisiel W, Podolak I, Galanty A, Trojanowska D. Steroidal glycosides from the underground parts of Allium ursinum L. and their cytostatic and antimicrobial activity. Acta Pol Pharm 2006; 63(3): 219-23.
[PMID: 20085228]
Janeczko Z, Sobolewska D, Podolak I. Pregnadienolone glycoside from wild garlic Allium ursinum L. Acta Pol Pharm 2000; 57(2): 131-3.
[PMID: 10934793]
Carotenuto A, De Feo V, Fattorusso E, Lanzotti V, Magno S, Cicala C. The flavonoids of Allium ursinum. Phytochemistry 1996; 41(2): 531-6.
[] [PMID: 8821433]
El Haouari M, Rosado JA. Medicinal plants with antiplatelet activity. Phytother Res 2016; 30(7): 1059-71.
[] [PMID: 27062716]
Wu H, Dushenkov S, Ho CT, Sang S. Novel acetylated flavonoid glycosides from the leaves of Allium ursinum. Food Chem 2009; 115(2): 592-5.
Štajner D, Milić N, Canadanović-Brunet J, Kapor A, Štajner M, Popović BM. Exploring Allium species as a source of potential medicinal agents. Phytother Res 2006; 20: 581-4.
Vlase L, Parvu M, Parvu EA, Toiu A. Phytochemical analysis of Allium fistulosum L. and A. ursinum L. Dig J Nanomater Biostruct 2012; 8(1): 457-67.
Condrat D, Mosoarca C, Zamfir AD, Crişan F, Szabo MR, Lupea AX. Qualitative and quantitative analysis of gallic acid in Alchemilla vulgaris, Allium ursinum, Acorus calamus and Solidago virga-aurea by chip-electrospray ionization mass spectrometry and high performance liquid chromatography. Cent Eur J Chem 2010; 8(3): 530-5.
Lachowicz S, Kolniak-Ostek J, Oszmiański J, Wiśniewski R. Comparison of phenolic content and antioxidant capacity of bear garlic (Allium ursinum L.) in different maturity stages. J Food Process Preserv 2017; 41(e12921): 1-6.
Ivanova A, Mikhova B, Najdenski H, Tsvetkova I, Kostova I. Chemical composition and antimicrobial activity of wild garlic Allium ursinum of Bulgarian origin. Nat Prod Commun 2009; 4(8): 1059-62.
[] [PMID: 19768983]
Parvu M, Toiu A, Vlase L, Alina Parvu E. Determination of some polyphenolic compounds from Allium species by HPLC-UV-MS. Nat Prod Res 2010; 24(14): 1318-24.
[] [PMID: 20419559]
Condrat D, Crisan F, Szabo M, Chambree D, Lupea A. Flavonoids in Angiospermatophyta and Spermatophyta Species and their Antioxidant Activity. Rev Chim 2009; 60(11): 1129-34.
Oszmiański J, Kolniak-Ostek J, Wojdyło A. Characterization and content of flavonol derivatives of Allium ursinum L. plant. J Agric Food Chem 2013; 61(1): 176-84.
[] [PMID: 23249145]
Hiyasat B, Sabha D, Grötzinger K, et al. Antiplatelet activity of Allium ursinum and Allium sativum. Pharmacology 2009; 83(4): 197-204.
[] [PMID: 19174616]
Xu XY, Song GQ, Yu YQ, Ma HY, Ma L, Jin YN. Apoptosis and G2/M arrest induced by Allium ursinum (ramson) watery extract in an AGS gastric cancer cell line. OncoTargets Ther 2013; 6: 779-83.
[] [PMID: 23836991]
Korga A, Ostrowska M, Iwan M, et al. Ethanol extracts of Allium sp. regulate cyclooxygenase-2 and E-cadherin expression in gastric cancer MKN74 cell line and enhance doxorubicin toxicity. Food Nutr Res 2019; 63(3449): 1-8.
[] [PMID: 31297043]
Mueller M, Jungbauer A. Culinary plants, herbs and spices - A rich source of PPAR?? Ligands Food Chem 2009; 117(4): 660-7.
Bârlă GF, Poroch-Seriţan M. Sănduleac Tudosi E, Ciornei Ştefăroi SE. Antioxidant activity and total phenolic content in Allium ursinum and Ranunculus ficaria. Food Environ Saf 2014; 13(4): 349-53.
Hřibová P, Khazneh E, Žemlička M, et al. Antiurease activity of plants growing in the Czech Republic. Nat Prod Res 2014; 28(12): 868-73.
[] [PMID: 24579848]
Krovánková SŠ, Mlček J, Snopek L, Planetová T. Polyphenols and antioxidant capacity in different types of garlic. Potravin Slovak J Food Sci 2018; 12(1): 267-72.
Lenková M, Bystrická J, Tóth T, Hrstková M. Evaluation and comparison of the content of total polyphenols and antioxidant activity of selected species of the genus Allium. J Cent Eur Agric 2016; 17(4): 1119-33.
Pejatović T, Samardžic D, Krivokapić S. Antioxidative properities of a traditional tincture and several leaf extracts of Allium ursinum L. (collected in Montenegro and Bosnia and Herzegovina). J Mater Environ Sci 2017; 8(6): 1929-34.
Pavlović DR, Veljković M, Stojanović NM, et al. Influence of different wild-garlic (Allium ursinum) extracts on the gastrointestinal system: spasmolytic, antimicrobial and antioxidant properties. J Pharm Pharmacol 2017; 69(9): 1208-18.
[] [PMID: 28543032]
Lupoae M, Coprean D, Dinicǎ R, Lupoae P, Gurau G, Bahrim G. Antimicrobial activity of extracts of wild garlic (Allium ursinum) from Romanian spontaneous flora. Sci Study Res Chem Chem Eng Biotechnol Food Ind 2013; 14(4): 221-7.
Gîtin L, Dinicǎ R, Parnavel R. The influence of extraction method on the apparent content of bioactive compounds in Romanian Allium spp. leaves. Not Bot Horti Agrobot Cluj-Napoca 2012; 40(1): 93-7.
Tomšik A, Šarić L, Bertoni S, et al. Encapsulations of wild garlic (Allium ursinum L.) extract using spray congealing technology. Food Res Int 2019; 119: 941-50.
[] [PMID: 30884734]
Radusin T, Torres-Giner S, Stupar A, et al. Preparation, characterization and antimicrobial properties of electrospun polylactide films containing Allium ursinum L. extract. Food Packag Shelf Life 2019; 21 100357
Mihaylova DS, Lante A, Tinello F, Krastanov AI. Study on the antioxidant and antimicrobial activities of Allium ursinum L. pressurised-liquid extract. Nat Prod Res 2014; 28(22): 2000-5.
[] [PMID: 24895887]
Bombicz M, Priksz D, Varga B, et al. Anti-atherogenic properties of Allium ursinum liophylisate: Impact on lipoprotein homeostasis and cardiac biomarkers in hypercholesterolemic rabbits. Int J Mol Sci 2016; 17: 1284.
[] [PMID: 27517918]
Bombicz M, Priksz D, Varga B, et al. A novel therapeutic approach in the treatment of pulmonary arterial hypertension: Allium ursinum liophylisate alleviates symptoms comparably to sildenafil. Int J Mol Sci 2017; 18: 1436.
[] [PMID: 28677661]
Preuss HG, Clouatre D, Mohamadi A, Jarrell ST. Wild garlic has a greater effect than regular garlic on blood pressure and blood chemistries of rats. Int Urol Nephrol 2001; 32(4): 525-30.
[] [PMID: 11989540]
Lachowicz S, Oszmiański J, Wiśniewski R. Determination of triterpenoids, carotenoids, chlorophylls, and antioxidant capacity in Allium ursinum L. at different times of harvesting and anatomical parts. Eur Food Res Technol 2018; 244(7): 1269-80.
Sabha D, Hiyasat B, Grötzinger K, et al. Allium ursinum L.: bioassay-guided isolation and identification of a galactolipid and a phytosterol exerting antiaggregatory effects. Pharmacology 2012; 89(5-6): 260-9.
[] [PMID: 22507958]
Petkova NT, Ivanov IG, Raeva M, Topuzova MG, Todorova MM, Denev PP. Fructans and antioxidants in leaves of culinary herbs from Asteraceae and Amaryllidaceae families. Food Res 2019; 3(5): 407-15.
Fierascu R, Ion R, Fierascu I. Antifungal effect of natural extracts on environmental biodeteriogens afecting artifacts. Environ Eng Manag J 2017; 16(11): 2435-42.
Nikkhahi M, Souri E, Sarkhail P, Baeeri M, Mohammadhosseini N. Evaluation of anti-tyrosinase activity of Allium ursinum extracts and their metal complexes. Acta Sci Pol Technol Aliment 2018; 17(3): 219-26.
[PMID: 30269461]
Vafaee K, Dehghani S, Tahmasvand R, Saeed Abadi F, Irian S, Salimi M. Potent antitumor property of Allium bakhtiaricum extracts. BMC Complement Altern Med 2019; 19(1): 116.
[] [PMID: 31164129]
Gholipour N, Mashjoor S, Naderi M, et al. In vitro cytotoxic and apoptotic activities of Allium paradoxum (M. bieb.) G. Don extract on human breast cancer cell line. Indian J Tradit Knowl 2018; 17(2): 247-54.
Motamed SM, Naghibi F. Antioxidant activity of some edible plants of the Turkmen Sahra region in northern Iran. Food Chem 2010; 119(4): 1637-42.
Ghavam-Haghi F, Dinani MS. Isolation and identification of Astragalin and 2-methoxy tyrosol from the bulbs of Allium paradoxum. J HerbMed Pharmacol 2017; 6(3): 114-8.
Nabavi SF, Nabavi SM, Moghaddam AH, Naqinezhad A, Bigdellou R, Mohammadzadeh S. Protective effects of Allium paradoxum against gentamicin-induced nephrotoxicity in mice. Food Funct 2012; 3(1): 28-9.
[] [PMID: 22033806]
Nabavi SM, Hajizadeh Moghaddam A, Fazli M, et al. Hepatoprotective activity of Allium paradoxum. Eur Rev Med Pharmacol Sci 2012; 16(Suppl. 3): 43-6.
[PMID: 22957417]
Ebrahimzadeh MA, Nabavi SF, Nabavi SM, Eslami B. Antihemolytic and antioxidant activities of Allium paradoxum. Cent Eur J Biol 2010; 5(3): 338-45.
Ebrahimzadeh MA, Taheri MM, Ahmadpour E, et al. Anti-Toxoplasma effects of methanol extracts of Feijoa sellowiana, Quercus castaneifolia, and Allium paradoxum. J Pharmacopuncture 2017; 20(3): 220-6.
[] [PMID: 30087799]
Nazer MR, Abbaszadeh S, Anbari K, Shams M. A review of the most important medicinal herbs affecting giardiasis. J HerbMed Pharmacol 2019; 8(2): 78-84.
Dehghan H, Sarrafi Y, Salehi P. Antioxidant and antidiabetic activities of 11 herbal plants from Hyrcania region, Iran. Yao Wu Shi Pin Fen Xi 2016; 24(1): 179-88.
[] [PMID: 28911402]
Rahimi-Esboei B, Ghorbani A, Gholami S, et al. Antiparasitic effects of Aliium paradoxum as a conventional consumed vegetable. Afr J Microbiol Res 2014; 8(31): 2979-83.
Arulselvan P, Karthivashan G, Fakurazi S. Hepatoprotective nature of phytoextracts against hepatotoxin induced animal models: A review. J Chem Pharm Res 2013; 5(7): 233-9.
Nabavi SF, Nabavi SM, Ebrahimzadeh MA, Eslami B, Jafari N. In vitro antioxidant and antihemolytic activities of hydroalcoholic extracts of Allium scabriscapum Boiss. & Ky. aerial parts and bulbs. Int J Food Prop 2013; 16(4): 713-22.
Chehregani A, Azimishad F, Alizade H. Study on Antibacterial effect of some Allium species from Hamedan-Iran. Int J Agric Biol 2007; 9: 873-6.
Assadpour S, Nabavi SM, Nabavi SF, Dehpour AA, Ebrahimzadeh MA. In vitro antioxidant and antihemolytic effects of the essential oil and methanolic extract of Allium rotundum L. Eur Rev Med Pharmacol Sci 2016; 20(24): 5210-5.
[PMID: 28051246]
Tepe B, Sokmen M, Akpulat HA, Sokmen A. In vitro antioxidant activities of the methanol extracts of five Allium species from Turkey. Food Chem 2005; 92(1): 89-92.
Shahbazi Y. Antibacterial and antioxidant properties of methanolic extracts of some native edible plants collected from Kermanshah, Western Iran. J Food Qual Hazards Control 2017; 4(4): 93-8.
Dehpour AA, Yousefian M, Jafary Kelarijani SA, et al. Antibacterial activity and composition of essential oils of flower Allium rotundum. Adv Environ Biol 2012; 6(3): 1024-5.
Maisashvili MR, Eristavi LI, Gvazava LN, Gugunishvili DM. Steroidal sapogenins from Allium rotundum. Chem Nat Compd 2007; 43(6): 756-7.
Maisashvili MR, Kuchukhidze DK, Gvazava LN, Eristavi LI. Steroidal glycosides from Allium rotundum. Chem Nat Compd 2008; 44(4): 545-7.
Mollica A, Zengin G, Locatelli M, Picot-Allain CMN, Mahomoodally MF. Multidirectional investigations on different parts of Allium scorodoprasum L. subsp. rotundum (L.) Stearn: Phenolic components, in vitro biological, and in silico propensities. Food Res Int 2018; 108(February): 641-9.
[] [PMID: 29735100]
Maisashvili MR, Kuchukhidze DK, Gvazava LN. Carotinoids and amino acids from Allium rotundum. Chem Nat Compd 2009; 45(5): 769-70.
Maisashvili MR, Gvazava LN, Kuchukhidze JK. Flavonoids and coumarins from Allium rotundum. Chem Nat Compd 2009; 45(1): 87-8.
Hosseinzadeh L, Farhangian S, Hajialyani M, Bahari A, Farzaei MH. Acute and subchronic toxicological evaluations of Allium rotundum L.: A dietary plant from Iran. J Diet Suppl 2019; 16(3): 269-80.
[] [PMID: 29694254]
Goorani S, Shariatifar N, Seydi N, et al. The aqueous extract of Allium saralicum R.M. Fritsch effectively treat induced anemia: experimental study on Wistar rats. Orient Pharm Exp Med 2019; 19: 403-13.
Zangeneh MM, Goodarzi N, Zangeneh A, Tahvilian R, Najafi F. Amelioration of renal structural changes in STZ-induced diabetic mice with ethanolic extract of Allium saralicum R.M. Fritsch. Comp Clin Pathol 2018; 27(4): 861-7.
Sherkatolabbasieh H, Hagh-Nazari L, Shafiezadeh S, Goodarzi N, Zangeneh MM, Zangeneh A. Ameliorative effects of the ethanolic extract of Allium saralicum R.M. Fritsch on CCl4-induced nephrotoxicity in mice: A stereological examination. Arch Biol Sci 2017; 69(4): 753-3.
Zhaleh M, Zangeneh MM, Zangeneh A, Moradi R, Zhaleh H. Antioxidant, cytotoxic, and wound healing effects of Allium saralicum RM Fritsch aqueous extract ointment in male rats: a gross, histological, and biochemical experiment. Comp Clin Pathol 2019; 28: 1421-9.
Jalalvand AR, Zhaleh M, Goorani S, et al. Chemical characterization and antioxidant, cytotoxic, antibacterial, and antifungal properties of ethanolic extract of Allium Saralicum R.M. Fritsch leaves rich in linolenic acid, methyl ester. J Photochem Photobiol B 2019; 192: 103-12.
[] [PMID: 30731424]
Khanahmadi M, Rezazadeh S, Shahrezaei F, Taran M, Rezaei M. Study on chemical composition of the essential oil, antimicrobial and antioxidant activities of Allium latifolium Gilib. (Liliaceae) extract. J Essent Oil-Bearing Plants 2011; 14(3): 345-53.
Qadir MI, Manzoor A, Akash MSH. Potential role of medicinal plants for anti-atherosclerosis activity. Bangladesh J Pharmacol 2018; 13(1): 59-66.
Sadeghi M, Safaeian L, Ghazvini MA, Ramezani M. Evaluation of fibrinolytic and antioxidant effects of Allium affine hydroalcoholic extract. Res Pharm Sci 2017; 12(4): 299-306.
[] [PMID: 28855941]
Hu XP, Zhou H, Du YM, Ou SY, Yan R, Wang Y. Two new flavonoids from the bark of Allium chrysanthum. J Asian Nat Prod Res 2017; 19(3): 229-34.
[] [PMID: 27310808]
El Shabrawy MOA, Hosni HA, El Garf IA, Marzouk MM, Kawashty SA, Saleh NAM. Flavonoids from Allium myrianthum Boiss. Biochem Syst Ecol 2014; 56: 125-8.
Barile E, Bonanomi G, Antignani V, et al. Saponins from Allium minutiflorum with antifungal activity. Phytochemistry 2007; 68(5): 596-603.
[] [PMID: 17118413]
Zolfaghari B, Shokoohinia Y, Ramezanlou P, Sadeghi A, Mahmoudzadeh M, Minaiyan M. Effects of methanolic and butanolic fractions of Allium elburzense Wendelbo bulbs on blood glucose level of normal and STZ-induced diabetic rats. Res Pharm Sci 2012; 7(4): 201-7.
[PMID: 23248670]
Safaeian L, Zolfaghari B, Karimi S, Talebi A, Ghazvini MA. The effects of hydroalcoholic extract of Allium elburzense Wendelbo bulb on dexamethasone-induced dyslipidemia, hyperglycemia, and oxidative stress in rats. Res Pharm Sci 2018; 13(1): 22-9.
[] [PMID: 29387108]
Akhov LS, Musienko MM, Piacente S, Pizza C, Oleszek W. Structure of steroidal saponins from underground parts of Allium nutans L. J Agric Food Chem 1999; 47(8): 3193-6.
[] [PMID: 10552629]
Mostafa A, Sudisha J, El-Sayed M, et al. Aginoside saponin, a potent antifungal compound, and secondary metabolite analyses from Allium nigrum L. Phytochem Lett 2013; 6(2): 274-80.
Kuroda M, Ori K, Takayama H, Sakagami H, Mimaki Y. Karataviosides G-K, five new bisdesmosidic steroidal glycosides from the bulbs of Allium karataviense. Steroids 2015; 93: 96-104.
[] [PMID: 25449766]
Mimaki Y, Kuroda M, Fukasawa T, Sashida Y. Steroidal saponins from the bulbs of Allium karataviense. Chem Pharm Bull (Tokyo) 1999; 47(6): 738-43.
[] [PMID: 10399831]
Selyutina IY, Tankhaeva LM, Olennikov DN. Acylated kaempferol diglycoside from Allium senescens. Chem Nat Compd 2008; 44(6): 769-70.
Inoue T, Mimaki Y, Sashida Y, Nishino A, Satomi Y, Nishino H. Steroidal glycosides from Allium macleanii and A. senescens, and their inhibitory activity on tumour promoter-induced phospholipid metabolism of HeLa cells. Phytochemistry 1995; 40(2): 521-5.
[] [PMID: 7546561]
Chung MS. Volatile compounds of the cultivated dumebuchu (Allium senescens L. var. senescens). Food Sci Biotechnol 2010; 19(6): 1679-82.
Vlase L, Parvu M, Parvu EA, Toiu A. Chemical constituents of three Allium species from Romania. Molecules 2012; 18(1): 114-27.
[] [PMID: 23344191]
Shin GM, Koppula S, Chae YJ, et al. Anti-hepatofibrosis effect of Allium senescens in activated hepatic stellate cells and thioacetamide-induced fibrosis rat model. Pharm Biol 2018; 56(1): 632-42.
[] [PMID: 31070527]
Pârvu M, Pârvu AE, Vlase L, Rosca-Casian O, Pârvu O, Puşcaş M. Allicin and alliin content and antifungal activity of Allium senescens L. ssp. montanum (F. W. Schmidt) Holub ethanol extract. J Med Plants Res 2011; 5(29): 6544-9.
Wang J, Wang N, Yao X, Ishii R, Kitanaka S. Inhibitory activity of Chinese herbal medicines toward histamine release from mast cells and nitric oxide production by macrophage-like cell line, RAW 264.7. J Nat Med 2006; 60(1): 73-7.
Ceylan O, Alic H. Antibiofilm, antioxidant, antimutagenic activities and phenolic compounds of Allium orientale BOISS. Braz Arch Biol Technol 2015; 58(6): 935-43.
Aydin Ç, Özay C, Mammadov R. Determination of antioxidant activities of two endemic allium species from turkey: A. sibthorpianum and A. Stylosum. J Appl Biol Sci 2015; 9(2): 31-6.
Karaaslan NM, Ince M, Kaplan Ince O, Goksin Karaaslan M. Determination of antioxidant capacity using different acidified solvents and element contents of Allium tuncelianum: A regional and varietal study on endemic edible garlic. Instrum Sci Technol 2019; 47(4): 423-35.
Yumrutaş Ö, Demirörs Saygideǧer S, Doǧan M. The in vitro antioxidant activity of Allium tuncelianum: An endemic. J Appl Biol Sci 2009; 3(3): 61-4.
Metiner K, Özkan O, Ak S. in Vitro Antibacterial and antifungal activity of Allium tuncelianum extract. Glob Vet 2016; 16(1): 26-30.
Özkan O, Gül S, Kart A, Çiçek BA, Kiliç K. In Vitro Antimutagenicity of Allium tuncelianum ethanol extract against induction of chromosome aberration by mutagenic agent mitomycine C. Kafkas Univ Vet Fak Derg 2013; 19(2): 259-62.
Ozusaglam MA, Darilmaz DO, Erzengin M, Teksen M, Erkul SK. Antimicrobial and antioxidant activities of two endemic plants from Aksaray in Turkey. Afr J Tradit Complement Altern Med 2013; 10(3): 449-57.
[] [PMID: 24146474]
Lorigooini Z, Ayatollahi SA, Amidi S, Kobarfard F. Evaluation of anti-platelet aggregation effect of some Allium species. Iran J Pharm Res 2015; 14(4): 1225-31.
[PMID: 26664390]
Khazaei S, Esa NM, Ramachandran V, et al. In vitro antiproliferative and apoptosis inducing effect of Allium atroviolaceum bulb extract on breast, cervical, and liver cancer cells. Front Pharmacol 2017; 8: 5.
[] [PMID: 28197098]
Khazaei S, Abdul Hamid R, Ramachandran V, et al. Cytotoxicity and proapoptotic effects of allium atroviolaceum flower extract by modulating cell cycle arrest and caspase-dependent and p53 - independent pathway in breast cancer cell lines. Evidence-based Complement Altern Med. 2017; 1-16.
Khazaei S, Ramachandran V, Abdul Hamid R, et al. Flower extract of Allium atroviolaceum triggered apoptosis, activated caspase-3 and down-regulated antiapoptotic Bcl-2 gene in HeLa cancer cell line. Biomed Pharmacother 2017; 89: 1216-26.
[] [PMID: 28320088]
Ghasemi S, Lorigooini Z, Wibowo J, Amini-Khoei H. Tricin isolated from Allium atroviolaceum potentiated the effect of docetaxel on PC3 cell proliferation: role of miR-21. Nat Prod Res 2019; 33(12): 1828-31.
[] [PMID: 29447469]
Zolfaghari B, Sadeghi M, Troiano R, Lanzotti V. Vavilosides A1/A2-B1/B2, new furostane glycosides from the bulbs of Allium vavilovii with cytotoxic activity. Bioorg Med Chem 2013; 21(7): 1905-10.
[] [PMID: 23415085]
Alagarsamy S, Chellappan P, Jesuraj MT, Mohan MSG, Balakrishnan R. Phytochemical analysis and antioxidant potential of the crude extract of Allium oschaninii scape. Orient Pharm Exp Med 2018; 18(4): 309-16.
Lu X, Wang J, Al-Qadiri HM, et al. Determination of total phenolic content and antioxidant capacity of onion (Allium cepa) and shallot (Allium oschaninii) using infrared spectroscopy. Food Chem 2011; 129(2): 637-44.
[] [PMID: 30634280]
Andersen ØM, Fossen T. Anthocyanins with an unusual acylation pattern from stem of Allium victorialis. Phytochemistry 1995; 40(6): 1809-12.
Nishimura H, Hanny Wijaya C, Mizutani J. Volatile flavor components and antithrombotic agents: Vinyldithiins from Allium victorialis L. J Agric Food Chem 1988; 36(3): 563-6.
Park H-J, Jung H-J, Lim S-C, et al. Antihepatotoxic effect of heat-treated Allium victorialis var. platyphyllum in CCl4-induced rats and the gas chromatographic analysis of volatile sulfur substances. Nat Prod Sci 2005; 11(2): 67-74.Available at:.
Khan S, Fatima I, Hussain Kazmi M, Malik A. New secondary metabolites from Allium victorialis. Helv Chim Acta 2013; 96(6): 1176-81.
Khan S, Fatima I, Kazmi MH, Malik A. A New steroidal alkaloid from Allium victorialis. Chem Nat Compd 2015; 51(6): 1134-7.
Khan S, Mehmood R, Kazmi MH, Malik A. Alliumonoate: a new cyclopentane derivative from Allium victorialis. J Asian Nat Prod Res 2011; 13(12): 1165-9.
[] [PMID: 21995684]
Woo KW, Moon E, Park SY, Kim SY, Lee KR. Flavonoid glycosides from the leaves of Allium victorialis var. platyphyllum and their anti-neuroinflammatory effects. Bioorg Med Chem Lett 2012; 22(24): 7465-70.
[] [PMID: 23149227]
Aslam MS, Ahmad MS, Mamat AS. A review on phytochemical constituents and pharmacological properties of Allium victorialis. Int J Pharm Pharm Sci 2019; 10(6): 278-88.
Woo KW, Lee KR. Phytochemical constituents of Allium victorialis var. platyphyllum. Nat Prod Sci 2013; 19(3): 221-6.
Lee KT, Choi JH, Kim DH, et al. Constituents and the antitumor principle of Allium victorialis var. platyphyllum. Arch Pharm Res 2001; 24(1): 44-50.
[] [PMID: 11235811]
Kim YS, Jung DH, Lee IS, et al. Effects of Allium victorialis leaf extracts and its single compounds on aldose reductase, advanced glycation end products and TGF-β1 expression in mesangial cells. BMC Complement Altern Med 2013; 13: 251.
[] [PMID: 24090434]
Shirataki Y, Motohashi N, Tani S, et al. Antioxidative activity of Allium victorialis L. extracts. Anticancer Res 2001; 21(5): 3331-9.Available at:.
[PMID: 11848491]
Golubkina NA, Nadezhkin SM, Agafonov AF, et al. Seed oil content, fatty acids composition and antioxidant properties as affected by genotype in Allium cepa L. and perennial onion species. Adv Hortic Sci 2015; 29(4): 199-206.
Isbilen O, Rizaner N, Volkan E. Anti-proliferative and cytotoxic activities of Allium autumnale P. H. Davis (Amaryllidaceae) on human breast cancer cell lines MCF-7 and MDA-MB-231. BMC Complement Altern Med 2018; 18(1): 30.
[] [PMID: 29370794]
Bazzaz BSF, Azadbakht M, Doust MS. Antibacterial activity of essential oils of Iranian plants (Mazandaran Province). J Essent Oil-Bearing Plants 2008; 11(4): 436-42.
Mohsenzadeh A, Ahmadipour S, Ahmadipour S, Asadi-Samani M. A review of the most important medicinal plants effective on cough in children and adults. Der Pharm Lett 2016; 8(1): 90-6.
Karimi M, Mardani M. Wound antiseptic plants: An overview of the most important medicinal plants in iran affecting wound infections. J Glob Pharma Technol 2016; 8(8): 18-23.
Zarei L, Naji-Haddadi S, Pourjabali M, Naghdi N, Tasbih-Forosh M, Shahsavari S. Systematic review of anti-rheumatic medicinal plants: An overview of the effectiveness of articular tissues and joint pain associated with rheumatoid arthritis. J Pharm Sci Res 2017; 9(5): 547-51.
Mohsenzadeh A, Ahmadipour S, Ahmadipour S, Eftekhari Z. A review of medicinal herbs affects the kidney and bladder stones of children and adults in traditional medicine and ethno-botany of Iran. Der Pharm Lett 2015; 7(12): 279-84.
Nencini C, Cavallo F, Capasso A, Franchi GG, Giorgio G, Micheli L. Evaluation of antioxidative properties of Allium species growing wild in Italy. Phytother Res 2007; 21(9): 874-8.
[] [PMID: 17514631]
Štajner D, Popović BM, Canadanović-Brunet J. Igić R. Antioxidant and scavenger activities of Allium ursinum. Fitoterapia 2008; 79: 303-5.
Zolfaghari B, Sadeghi M, Troiano R, Lanzotti V. 3,4-Seco-spirostane sapogenins with cytotoxic activity from Allium umbilicatum boiss. Phytochem Lett 2015; 12: 291-5.
Sadeghi M, Zolfaghari B, Troiano R, Lanzotti V. 3-Keto umbilicagenin A and B, new sapogenins from Allium umbilicatum Boiss. Fitoterapia 2015; 102: 198-202.
[] [PMID: 25579389]
Lee S, Kim DH, Lee CH, et al. Antidepressant-like activity of the aqueous extract of Allium macrostemon in mice. J Ethnopharmacol 2010; 131(2): 386-95.
[] [PMID: 20637276]
Chen S, Wei C, Gao P, et al. Effect of Allium macrostemon on a rat model of depression studied by using plasma lipid and acylcarnitine profiles from liquid chromatography/mass spectrometry. J Pharm Biomed Anal 2014; 89: 122-9.
[] [PMID: 24284228]
Liu XC, Liu Q, Zhou L, Liu ZL. Evaluation of larvicidal activity of the essential oil of Allium macrostemon Bunge and its selected major constituent compounds against Aedes albopictus (Diptera: Culicidae). Parasit Vectors 2014; 7(184): 184.
[] [PMID: 24731297]
Chen HF, Wang GH, Luo Q, Wang NL, Yao XS. Two new steroidal saponins from Allium macrostemon bunge and their cytotoxity on different cancer cell lines. Molecules 2009; 14(6): 2246-53.
[] [PMID: 19553896]
Chen H, Wang G, Wang N, et al. New furostanol saponins from the bulbs of Allium macrostemon Bunge and their cytotoxic activity. Pharmazie 2007; 62(7): 544-8.
[PMID: 17718198]
Kim YS, Cha JM, Kim DH, Lee TH, Lee KR. A new steroidal glycoside from Allium macrostemon Bunge. Nat Prod Sci 2018; 24(1): 54-8.
Chen H, Ou W, Wang G, Wang N, Zhang L, Yao X. New steroidal glycosides isolated as CDL inhibitors of activated platelets. Molecules 2010; 15(7): 4589-98.
[] [PMID: 20657379]
Chen HF, Wang NL, Sun HL, Yang BF, Yao XS. Novel furostanol saponins from the bulbs of Allium macrostemon B. and their bioactivity on [Ca2+]i increase induced by KCl. J Asian Nat Prod Res 2006; 8(1-2): 21-8.
[] [PMID: 16753778]
Xie W, Zhang Y, Wang N, et al. Novel effects of macrostemonoside A, a compound from Allium macrostemon Bung, on hyperglycemia, hyperlipidemia, and visceral obesity in high-fat diet-fed C57BL/6 mice. Eur J Pharmacol 2008; 599(1-3): 159-65.
[] [PMID: 18930725]
Wang Y, Tang Q, Jiang S, Li M, Wang X. Anti-colorectal cancer activity of macrostemonoside A mediated by reactive oxygen species. Biochem Biophys Res Commun 2013; 441(4): 825-30.
[] [PMID: 24211203]
Feng H, Wang Z, Wang C, et al. Effect of furostanol saponins from Allium Macrostemon Bunge bulbs on platelet aggregation rate and PI3K/Akt pathway in the rat model of coronary heart disease. Evidence-based Complement Altern Med 2019; pp. 1-7.
Han C, Qi J, Gao S, et al. Vasodilation effect of volatile oil from Allium macrostemon Bunge are mediated by PKA/NO pathway and its constituent dimethyl disulfide in isolated rat pulmonary arterials. Fitoterapia 2017; 120: 52-7.
[] [PMID: 28552597]
Zhou H, Yang X, Wang NL, Zhang YO, Cai GP. Macrostemonoside A promotes visfatin expression in 3T3-L1 cells. Biol Pharm Bull 2007; 30(2): 279-83.
[] [PMID: 17268065]
Zhang Z, Wang F, Wang M, Ma L, Zeng X. Extraction optimisation and antioxidant activities in vitro of polysaccharides from Allium macrostemon Bunge. Int J Food Sci Technol 2012; 47(4): 723-30.
Park HS, Choi EJ, Lee J-H, Kim G-H. Evaluation of Allium vegetables for anti-adipogenic, anti-cancer, and anti-inflammatory activities in vitro. J Life Sci 2013; 5(2): 127-32.
Demirci Kayiran S, Eroglu Ozkan E, Mataraci Kara E, Yilmaz MA, Zengin G, Boga M. Comprehensive analysis of an uninvestigated wild edible medicinal garlic species from Turkey: Allium macrochaetum Boiss. & Hausskn. J Food Biochem 2019; 43(7) e12928
[] [PMID: 31353714]
Sadiq A, Ahmad S, Ali R, et al. Antibacterial and antifungal potentials of the solvents extracts from Eryngium caeruleum, Notholirion thomsonianum and Allium consanguineum. BMC Complement Altern Med 2016; 16(1): 478.
[] [PMID: 27881119]
Shahriari M, Hemmati S, Zangeneh A, Zangeneh MM. Biosynthesis of gold nanoparticles using Allium noeanum Reut. ex Regel leaves aqueous extract; characterization and analysis of their cytotoxicity, antioxidant, and antibacterial properties. Appl Organomet Chem 2019; 1-11.
Taghavizadeh Yazdi ME, Hamidi A, et al. Eco-friendly and plant-based synthesis of silver nanoparticles using Allium giganteum and investigation of its bactericidal, cytotoxicity, and photocatalytic effects. Mater Technol 2019; 34(8): 490-7.
Tsuruoka T, Ishikawa K, Hosoe T, Davaajab D, Duvjir S, Surenjav U. A new cinnamoylphenethylamine derivative from a Mongolian Allium species, Allium carolinianum. J Nat Med 2018; 72(1): 332-4.
[] [PMID: 29063363]
Yatoo MI, Dimri U, Gopalakrishnan A, Saxena A, Wani SA, Dhama K. In vitro and in vivo immunomodulatory potential of Pedicularis longiflora and Allium carolinianum in alloxan-induced diabetes in rats. Biomed Pharmacother 2018; 97(97): 375-84.
[] [PMID: 29091887]
Wang W, Li J, Zhang H, Wang X, Fan J, Zhang X. Phenolic compounds and bioactivity evaluation of aqueous and methanol extracts of Allium mongolicum Regel. Food Sci Nutr 2019; 7(2): 779-87.
[] [PMID: 30847157]
Corea G, Fattorusso E, Lanzotti V. Saponins and flavonoids of Allium triquetrum. J Nat Prod 2003; 66(11): 1405-11.
[] [PMID: 14640509]
Mskhiladze L, Chincharadze D, Mshvildadze V, et al. Steroidal glycosides from the flowers of Allium leucanthum. Chem Nat Compd 2015; 51(5): 900-4.
Lazarević JS, Ethorđević AS, Zlatković BK, Radulović NS, Palić RM. Chemical composition and antioxidant and antimicrobial activities of essential oil of Allium sphaerocephalon L. subsp. sphaerocephalon (Liliaceae) inflorescences. J Sci Food Agric 2011; 91(2): 322-9.
[] [PMID: 20945514]
Rouis-Soussi LS, Ayeb-Zakhama AE, Mahjoub A, Flamini G, Jannet HB, Harzallah-Skhiri F. Chemical composition and antibacterial activity of essential oils from the Tunisian Allium nigrum L. EXCLI J 2014; 13: 526-35.
[PMID: 26417280]
Kusterer J, Vogt A, Keusgen M. Isolation and identification of a new cysteine sulfoxide and volatile sulfur compounds from Allium subgenus Melanocrommyum. J Agric Food Chem 2010; 58(1): 520-6.
[] [PMID: 19919098]
Kusterer J, Fritsch RM, Keusgen M. Allium species from Central and Southwest Asia are rich sources of marasmin. J Agric Food Chem 2011; 59(15): 8289-97.
[] [PMID: 21721585]
Maikhuri RK, Negi VS, Rawat LS, Pharswan DS. Bioprospecting of medicinal plants in Nanda Devi Biosphere Reserve: Linking conservation with livelihood. Curr Sci 2017; 113(4): 571-7.
Acharya K, Pokhrel H, Maharjan L, et al. Comparative Study of Antibacterial and cytotoxic activity of two nepalese medicinal plants- Allium wallichii Kunth and Allium sativum L. Int J Pharm Biol Arch 2011; 2(5): 1539-43.
Bhandari J, Muhammad B, Thapa P, Shrestha BG. Study of phytochemical, anti-microbial, anti-oxidant, and anti-cancer properties of Allium wallichii. BMC Complement Altern Med 2017; 17(1): 102.
[] [PMID: 28178952]
Dobhal Y, Parcha V, Dhasmana DC. Characterization of new cardioprotective principle isolated from methanolic extract of Allium humile leaves from Himalayan region. Bangladesh J Pharmacol 2016; 11(2): 383-8.
Dobhal Y, Parcha V, Dhasmana DC. Cardioprotective potential of Allium humile leaves extract. Orient Pharm Exp Med 2014; 14(2): 157-62.
Acharya J, Hildreth MB, Reese RN. In vitro screening of forty medicinal plant extracts from the United States Northern Great Plains for anthelmintic activity against Haemonchus contortus. Vet Parasitol 2014; 201(1-2): 75-81.
[] [PMID: 24548703]
Chen S, Snyder JK. Diosgenin-Bearing, Molluscicidal saponins from Allium vineale: An NMR approach for the structural assignment of oligosaccharide Units. J Org Chem 1989; 54(15): 3679-89.
Štajner D, Igić R, Popović BM, Malencić Dj. Comparative study of antioxidant properties of wild growing Allium species. Phytother Res 2008; 22: 113-7. journal/117934759/abstract
Štajner D, Milić N, Mimica-Dukić N, Lazić B, Igić R. Antioxidant abilities of cultivated and wild species of garlic. Phytother Res 1998; 12(Suppl. 1): 13-4.
Demirtas I, Erenler R, Elmastas M, Goktasoglu A. Studies on the antioxidant potential of flavones of Allium vineale isolated from its water-soluble fraction. Food Chem 2013; 136(1): 34-40.
[] [PMID: 23017389]
Durmaz H, Sagun E, Tarakci Z, Ozgokce F. Antibacterial activities of Allium vineale, Chaerophyllum macropodum and Prangos ferulacea. Afr J Biotechnol 2006; 5(19): 1795-8.
Degerli S, Berk S, Tepe B, Malatyali E. Amoebicidal activity of the rhizomes and aerial parts of Allium sivasicum on Entamoeba histolytica. Parasitol Res 2012; 111(1): 59-64.
[] [PMID: 22215196]
Tepe B, Tuncer E, Saraydın SU, et al. Antitumoral effects of Allium sivasicum on breast cancer in vitro and in vivo. Mol Biol Rep 2013; 40(1): 597-604.
[] [PMID: 23065225]
Polat ZA, Vural A, Tepe B, Cetin A. In vitro amoebicidal activity of four Allium species on Acanthamoeba castellanii and their cytotoxic potentials on corneal cells. Parasitol Res 2007; 101(2): 397-402.
[] [PMID: 17318581]
Mitic VD, Stankov-Jovanovic VP, Ilic MD, Cvetkovic JS, Dimitrijevic MV, Stojanovic GS. In vitro antioxidant activity of methanol extract of Allium scorodoprasum. Bulg J Agric Sci 2014; 20(5): 1130-6.
Mosavi H, Alizadeh A. Phytochemical constituents and antimicrobial activity of Allium Eriophyllum Var. Eriophyllum from Iran. Nat Prod Res 2019; 33(21): 3148-52.
[] [PMID: 30398370]
Kiralan M, Rahimi A, Arslan N, Bayrak A. Volatiles in an endemic Allium specie: Allium tuncelianum by headspace solid phase microextraction. J Essent Oil-Bearing Plants 2013; 16(3): 417-20.

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