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Current Pediatric Reviews


ISSN (Print): 1573-3963
ISSN (Online): 1875-6336

General Review Article

Vaccinations in Infants Born Preterm: An Update

Author(s): Areti Aphrodite Sioriki, Despoina Gkentzi, Evangelia Papadimitriou, Gabriel Dimitriou and Ageliki Karatza*

Volume 16 , Issue 2 , 2020

Page: [148 - 155] Pages: 8

DOI: 10.2174/1573396316666200116094459


Infants born prematurely (before completion of 37 weeks of gestation) are at increased risk of morbidity and mortality due to vaccine preventable diseases, mostly because of their immunological immaturity and failure of transfer of maternal protective antibodies. Despite their great need of being vaccinated, concerns on vaccine safety and efficacy, constitute the main reasons for which vaccinations are often delayed in this group. In this review we summarize the latest evidence on vaccine safety, efficacy and immunogenicity in preterm infants which is similar to full-term infants. Therefore there is no reason for delaying vaccination in this population.

Keywords: Vaccinations, immunization, premature infants, born, morbidity, mortality, immunogenicity.

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