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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Review Article

Repurposing Drugs for Skin Cancer

Author(s): Levon M. Khachigian*

Volume 27 , Issue 42 , 2020

Page: [7214 - 7221] Pages: 8

DOI: 10.2174/0929867327666191220103901

Price: $65

Abstract

Drug repurposing is the process of developing existing or abandoned drugs for a different disease. Repurposing can circumvent higher costs and times associated with conventional drug discovery strategies because toxicity and pharmacokinetics profiles are typically already established. This brief review focuses on efforts to repurpose drugs for skin cancer and includes reuse of antihypertensives, anthelmintics and antifungals among a range of other medicines. Repurposing not only ushers promising known drugs for new indications, the process of repurposing can uncover new mechanistic insights in the pathogenesis of disease and uncover new opportunities for pharmaceutical intervention.

Keywords: Drug repurposing, drug repositioning, melanoma, skin cancer, cancer, disease, melanoma.

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