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Current Medicinal Chemistry


ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

Review Article

Natural Polymer-based Stimuli-responsive Hydrogels

Author(s): Yuheng Jiang, Ying Wang, Qin Li , Chen Yu* and Wanli Chu*

Volume 27, Issue 16, 2020

Page: [2631 - 2657] Pages: 27

DOI: 10.2174/0929867326666191122144916

Price: $65


The abilities of intelligent polymer hydrogels to change their structure and volume phase in response to external stimuli have provided new possibilities for various advanced technologies and great research and application potentials in the medical field. The natural polymer-based hydrogels have the advantages of environment-friendliness, rich sources and good biocompatibility. Based on their responsiveness to external stimuli, the natural polymer-based hydrogels can be classified into the temperature-responsive hydrogel, pH-responsive hydrogel, light-responsive hydrogel, electricresponsive hydrogel, redox-responsive hydrogel, enzyme-responsive hydrogel, magnetic-responsive hydrogel, multi-responsive hydrogel, etc. In this review, we have compiled some recent studies on natural polymer-based stimuli-responsive hydrogels, especially the hydrogels prepared from polysaccharides. The preparation methods, properties and applications of these hydrogels in the medical field are highlighted.

Keywords: Smart hydrogels, Stimuli-responsive, Natural polymers, Polysaccharides, Chemical stimuli.

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