Generic placeholder image

Current Medical Imaging


ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

Case Report

Papillary Tumor of the Pineal Region with Parinaud Syndrome: A Case Report

Author(s): Lale Damgacı, Büşra Hayat* and Servet Güreşçi

Volume 16, Issue 8, 2020

Page: [1044 - 1047] Pages: 4

DOI: 10.2174/1573405615666191111143716

Price: $65


Backround: Less than 1% of all intracranial tumors are in the pineal region. Papillary tumor of the pineal region is considered one of four pineal parenchymal tumors according to the 2007 World Health Organisation classification of central nervous system tumors. It is mostly seen in the middle age and it is rare under the age of 17 in the literature. In this report, we aim to present a case with papillary tumor of the pineal region with both CT and MRI findings, and discuss the differential diagnosis.

Case report: A 17-year-old female patient who underwent a treatment of ventriculoperitoneal shunt due to hydrocephalus 18 months ago applied to the neurosurgery clinic with nausea, vomiting, sensorineural hearing loss and Parinaud syndrome continuing through 1 month. Computed tomography (CT) and magnetic resonance imaging (MRI) have been applied. A 58x31x38 mm mass with cystic and mild hyperdense soft tissue components was observed in the localization of pineal gland and posterior comissure on non-enhanced CT. MRI examination revealed that the mass filled the pineal region, contained solid and large cystic components, and hyperintense on T1-weighted images. After intravenous contrast media injection, the mass enhanced more peripherally. DW-MRI showed that there is a diffusion restriction in some parts of the soft tissue components. The mass was totally resected, and pathology report revealed that it is a papillary tumor of the pineal region.

Conclusion: When a T1-weighted hyperintense and CT hyperdense mass with cystic and solid components is seen in the pineal region, even if it is rare, papillary tumor should also be considered in the differential diagnosis after exclusion of other hyperintense lesions in T1-weighted imaging.

Keywords: Papillary tumour, Parinaud syndrome, pineal region, brain tumour, intracranial tumour, pineal gland tumour.

Graphical Abstract
Smith AB, Rushing EJ, Smirniotopoulos JG. From the archives of the AFIP: Lesions of the pineal region: radiologic-pathologic correlation. Radiographics 2010; 30(7): 2001-20.
[ ] [PMID: 21057132]
Jouvet A, Nakazato Y, Scheithauer BW, et al. Papillary tumour of the pineal region. In: Louis DN, Ohgaki H, Wiestler OD, et al (eds) World Health Organization classification of tumours of the nervous system IARC, Lyon pp 128-129, Lyon: IARC 2007.
Vandergriff C, Opatowsky M, O’Rourke B, Layton K. Papillary tumor of the pineal region. Proc Bayl Univ Med Cent 2012; 25(1): 78-9.
[] [PMID: 22275792]
Ribeiro BNF, Muniz BC, Ventura N, Gasparetto EL, Marchiori E. Papillary tumor of the pineal region accompanied by Parinaud’s syndrome: Magnetic resonance imaging findings. Radiol Bras 2018; 51(3): 202-4.
[ ] [PMID: 29991845]
Jouvet A, Fauchon F, Liberski P, et al. Papillary tumor of the pineal region. Am J Surg Pathol 2003; 27(4): 505-12.
[] [PMID: 12657936]
Dumrongpisutikul N, Intrapiromkul J, Yousem DM. Distinguishing between germinomas and pineal cell tumors on MR imaging. AJNR Am J Neuroradiol 2012; 33(3): 550-5.
[] [PMID: 22173760]
Ghesani M, Li C-D, Wallis S, et al. Papillary tumor of the pineal region. HemOnc Today 2012 January 10.
Chang AH, Fuller GN, Debnam JM, et al. MR imaging of papillary tumor of the pineal region. AJNR Am J Neuroradiol 2008; 29(1): 187-9.
[] [PMID: 17925365]

Rights & Permissions Print Export Cite as
© 2023 Bentham Science Publishers | Privacy Policy