Login Register Cart 0
Generic placeholder image

Current Drug Discovery Technologies

Editor-in-Chief

ISSN (Print): 1570-1638
ISSN (Online): 1875-6220

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Review Article

Moringa Oleifera in Malnutrition: A Comprehensive Review

Author(s): Bilal Sajid Mushtaq, Muhammad Bilal Hussain*, Rabia Omer, Hafiz Ahmad Toor, Marwa Waheed, Mohammad Ali Shariati, Plygun Sergey and Mojtaba Heydari

Volume 18, Issue 2, 2021

Published on: 05 November, 2019

Page: [235 - 243] Pages: 9

DOI: 10.2174/1570163816666191105162722

Price: $65

Abstract

Nutritional deficiency is a major concern in developing countries, resulting in serious health consequences like mental and physical growth retardation. Moringa oleifera (Moringa), a nutritious plant growing in tropical regions of developing countries, is a candidate for overcoming nutritional deficiency. Moringa leaves are rich in protein including sulphur containing amino acids. It contains high amounts of vitamin C than oranges, a higher concentration of vitamin A than carrots, higher calcium content than milk and more potassium than bananas. Moreover, there is 9 times more iron in moringa than spinach and 4 times more fiber than oats. This review enlightens and explores the nutritional diversification of Moringa oleifera and other benefits which make it a better choice to use in our daily diet to combat malnutrition.

Keywords: Moringaoleifera, malnutrition, medicinal plant, traditional medicine, nutritional diversification, developing countries.

Graphical Abstract

[1]
Ferreira PMP, Farias DF, Oliveira JTDA, Carvalho ADFU. Moringaoleifera: bioactive compounds and nutritional potential. Br J Nutr 2008; 21: 431-7.
[2]
Oduro I, Ellis W, Owusu D. Nutritional potential of two leafy vegetables: Moringaoleifera and Ipomoea batatas leaves Sci Res Essays 2008; 3: 057-60.
[3]
Wood J, Enser M, Fisher A, Nute G, Whittington F, Richardson R. Effects of diets on fatty acids and meat quality. Options Mediterranean Series A 2003; 67: 133-41.
[4]
Singh BN, Singh BR, Singh RL, et al. Oxidative DNA damage protective activity, antioxidant and anti-quorum sensing potentials of Moringa oleifera. Food Chem Toxicol 2009; 47(6): 1109-16.
[http://dx.doi.org/10.1016/j.fct.2009.01.034] [PMID: 19425184]
[5]
Anwar F, Bhanger MI. Analytical characterization of Moringa oleifera seed oil grown in temperate regions of Pakistan. J Agric Food Chem 2003; 51(22): 6558-63.
[http://dx.doi.org/10.1021/jf0209894] [PMID: 14558778]
[6]
Fahey JW. Moringaoleifera: A review of the medical evidence for its nutritional, therapeutic, and prophylactic properties. Part 1. Trees Life J 2005; 5: 1-24.
[7]
Mbikay M. Therapeutic potential of Moringaoleifera leaves in chronic hyperglycemia and dyslipidemia: a review. Front Pharmacol 2012; 3: 24.
[http://dx.doi.org/10.3389/fphar.2012.00024] [PMID: 22403543]
[8]
Golden MH. The development of concepts of malnutrition. J Nutr 2002; 132(7): 2117S-22S.
[http://dx.doi.org/10.1093/jn/132.7.2117S] [PMID: 12097705]
[9]
Hekmat S, Morgan K, Soltani M, Gough R. Sensory evaluation of locally-grown fruit purees and inulin fibre on probiotic yogurt in mwanza, Tanzania and the microbial analysis of probiotic yogurt fortified with Moringaoleifera. J Health Popul Nutr 2015; 33: 60-72.
[10]
Anwar F, Ashraf M, Bhanger MI. Interprovenance variation in the composition of Moringaoleifera oilseeds from Pakistan. J Am Oil Chem Soc 2005; 82: 45-51.
[http://dx.doi.org/10.1007/s11746-005-1041-1]
[11]
FAO/WHO. Food and Agricultural Organization and World Health Organization, Human Vitamin and Mineral Requirements Joint FAO/WHO expert Consultation on human vitamin and mineral requirements 2002; 305. FAO/WHO non-series Publication
[12]
UN United Nations Road Map Towards the Implementation of the United Nations Millennium. New York, USA: Declaration 2000.
[13]
Anwar F, Latif S, Ashraf M, Gilani AH. Moringa oleifera: a food plant with multiple medicinal uses. Phytother Res 2007; 21(1): 17-25.
[http://dx.doi.org/10.1002/ptr.2023] [PMID: 17089328]
[14]
Mouminah HHS. Effect of dried Moringaoleifera leaves on the nutritional and organoleptic characteristics of cookies. Alexandria Sci Exchange J 2015; 36: 297-302.
[15]
Singh RG, Negi PS, Radha C. Phenolic composition, antioxidant and antimicrobial activities of free and bound phenolic extracts of Moringaoleifera seed flour. J Funct Foods 2013; 5: 1883-91.
[http://dx.doi.org/10.1016/j.jff.2013.09.009]
[16]
Negin J, Burchi F, Fanzo J. Ensuring food security through integration ofagriculture, nutrition and health programs: Reexamining research and policy. J Agric Food Syst Community Dev 2011; 8: 358-73.
[17]
Paliwal R, Sharma V, Pracheta J. A review on horse radish tree (Moringaoleifera): A multipurpose tree with high economic and commercial importance. Asian J Biotechnol 2011; 3: 317-28.
[http://dx.doi.org/10.3923/ajbkr.2011.317.328]
[18]
Karim OR, Kayode RMO, Oyeyinka S, Oyeyinka AT. Proximate, mineral and sensory qualities of ‘Amala’ prepared from yam flour fortified with moringa leaf powder. Food Sci Quality Manag 2013; 12: 10-22.
[19]
Manaois RV, Morales AV, Abilgos-Ramos RG. Acceptability, shelf life and nutritional quality of moringa-supplemented rice crackers. Philipp J Crop Sci 2013; 38: 1-8.
[20]
Salem AS, Salama WM, Hassanein A, El Ghandour H. Enhancement of nutritional and biological values of Labneh by adding dry leaves of Moringaoleifera as innovative dairy products. World Appl Sci J 2013; 22: 1594-602.
[21]
Martin FW, Ruberte RM, Meitzner LS. Edible Leaves of the Tropics. 3rd ed. 1998.
[22]
Mutheeswaran S, Pandikumar P, Chellappandian M, Ignacimuthu S. Documentation and quantitative analysis of the local knowledge on medicinal plants among traditional Siddha healers in Virudhunagar district of Tamil Nadu, India. J Ethnopharmacol 2011; 137(1): 523-33.
[http://dx.doi.org/10.1016/j.jep.2011.06.003] [PMID: 21718779]
[23]
Nambiar VS, Seshadri S. Bioavailability trials of β-carotene from fresh and dehydrated drumstick leaves (Moringa oleifera) in a rat model. Plant Foods Hum Nutr 2001; 56(1): 83-95.
[http://dx.doi.org/10.1023/A:1008132503972] [PMID: 11213172]
[24]
Liu RH. Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicals. Am J Clin Nutr 2003; 78(3)(Suppl.): 517S-20S.
[http://dx.doi.org/10.1093/ajcn/78.3.517S] [PMID: 12936943]
[25]
Prakash D, Suri S, Upadhyay G, Singh BN. Total phenol, antioxidant and free radical scavenging activities of some medicinal plants. Int J Food Sci Nutr 2007; 58(1): 18-28.
[http://dx.doi.org/10.1080/09637480601093269] [PMID: 17415953]
[26]
Ayerza R. Seed yield components, oil content, and fatty acid composition of two cultivars of moringa (Moringaoleifera Lam.) growing in the Arid Chaco of Argentina. Ind Crops Prod 2011; 33: 389-94.
[http://dx.doi.org/10.1016/j.indcrop.2010.11.003]
[27]
Rao BN. Bioactive phytochemicals in Indian foods and their potential in health promotion and disease prevention. Asia Pac J Clin Nutr 2003; 12(1): 9-22.
[PMID: 12737006]
[28]
Siddhuraju P, Becker K. Antioxidant properties of various solvent extracts of total phenolic constituents from three different agroclimatic origins of drumstick tree (Moringa oleifera Lam.) leaves. J Agric Food Chem 2003; 51(8): 2144-55.
[http://dx.doi.org/10.1021/jf020444+] [PMID: 12670148]
[29]
Brisibe EA, Umoren UE, Brisibe F, et al. Nutritional characterization and antioxidant capacity of different tissues of Artemisia annual. Food Chem 2009; 115: 1240-6.
[http://dx.doi.org/10.1016/j.foodchem.2009.01.033]
[30]
Oyeyinka AT, Oyeyinka SA. Moringaoleifera as a food fortificant: recent trends and prospects. J Saudi Soc Agric Sci 2016; 3: 78-88.
[31]
Owusu D, Ellis WO, Oduro I. Nutritional potential of two leafy vegetables: Moringa oleifera and Ipomoea batatas leaves. Sci Res Essays 2008; 3: 57-60.
[32]
Barminas JT, Charles M, Emmanuel D. Mineral composition of non-conventional leafy vegetables. Plant Foods Hum Nutr (Formerly QualitasPlantarum) 1998; 53(1): 29-36.
[http://dx.doi.org/10.1023/A:1008084007189] [PMID: 10890755]
[33]
Amabye TG, Gebrehiwot K. Chemical compositions and nutritional value of Moringaoleifera available in the market of Mekelle. J Food Nutr Sci 2015; 3: 187-90.
[34]
Fuglie LJ. Combating malnutrition with Moringa. The miracle tree: the multiple attributes of Moringa CTA Publication, Wageningen, the Netherlands 2001; 33: 117-36.
[35]
Muhammad HI, Asmawi MZ, Khan NK. A review on promising phytochemical, nutritional and glycemic control studies on Moringaoleifera lam in tropical and sub-tropical regions. Asian Pac J Trop Biomed 2016; 6: 896-902.
[http://dx.doi.org/10.1016/j.apjtb.2016.08.006]
[36]
Chambial S, Dwivedi S, Shukla KK, John PJ, Sharma P. Vitamin C in disease prevention and cure: an overview. Indian J Clin Biochem 2013; 28(4): 314-28.
[http://dx.doi.org/10.1007/s12291-013-0375-3] [PMID: 24426232]
[37]
Borel P, Preveraud D, Desmarchelier C. Bioavailability of vitamin E in humans: an update. Nutr Rev 2013; 71(6): 319-31.
[http://dx.doi.org/10.1111/nure.12026] [PMID: 23731443]
[38]
CN. Standing Committee on Nutrition. In: Working together to end child hunger and under-nutrition SCN News No34, Geneva. 2007.
[39]
Alfaia CP, Alves SP, Martins SI, et al. Effect of the feeding system on intramuscular fatty acids and conjugated linoleic acid isomers of beef cattle, with emphasis on their nutritional value and discriminatory ability. Food Chem 2009; 114: 939-46.
[http://dx.doi.org/10.1016/j.foodchem.2008.10.041]
[40]
Yach D. Food companies and nutrition for better health. Public Health Nutr 2008; 11(2): 109-11.
[http://dx.doi.org/10.1017/S1368980007001619] [PMID: 18297759]
[41]
Bennett RN, Mellon FA, Foidl N, et al. Profiling glucosinolates and phenolics in vegetative and reproductive tissues of the multi-purpose trees Moringa oleifera L. (horseradish tree) and Moringa stenopetala L. J Agric Food Chem 2003; 51(12): 3546-53.
[http://dx.doi.org/10.1021/jf0211480] [PMID: 12769522]
[42]
Rashid U, Anwar F, Moser BR, Knothe G. Moringa oleifera oil: a possible source of biodiesel. Bioresour Technol 2008; 99(17): 8175-9.
[http://dx.doi.org/10.1016/j.biortech.2008.03.066] [PMID: 18474424]
[43]
Bajpai M, Pande A, Tewari SK, Prakash D. Phenolic contents and antioxidant activity of some food and medicinal plants. Int J Food Sci Nutr 2005; 56(4): 287-91.
[http://dx.doi.org/10.1080/09637480500146606] [PMID: 16096138]
[44]
Ahmed HH, Metwally FM, Rashad H, Zaazaa AM, Ezzat SM, Salama MM. Moringaoleifera off ers a multi-mechanistic approach for management of obesity in rats. Int J Pharm Sci Rev Res 2014; 29: 98-106.
[45]
Lin M, Zhang J, Chen X. Bioactive flavonoids in Moringa oleifera and their health-promoting properties. J Funct Foods 2018; 47: 469-79.
[http://dx.doi.org/10.1016/j.jff.2018.06.011]
[46]
Nandave M, Ojha SK, Joshi S, Kumari S, Arya DS. Moringa oleifera leaf extract prevents isoproterenol-induced myocardial damage in rats: evidence for an antioxidant, antiperoxidative, and cardioprotective intervention. J Med Food 2009; 12(1): 47-55.
[http://dx.doi.org/10.1089/jmf.2007.0563] [PMID: 19298195]
[47]
Sivasankari B, Anandharaj M, Gunasekaran P. An ethnobotanical study of indigenous knowledge on medicinal plants used by the village peoples of Thoppampatti, Dindigul district, Tamilnadu, India. J Ethnopharmacol 2014; 153(2): 408-23.
[http://dx.doi.org/10.1016/j.jep.2014.02.040] [PMID: 24583241]
[48]
Zhang M, Hettiarachchy NS, Horax R, Kannan A, Praisoody A, Muhundan A. Phytochemicals, antioxidant and antimicrobial activity of Hibiscus sabdariffa, Centellaasiatica, Moringaoleifera and Murrayakoenigii leaves. J Med Plants Res 2011; 5: 66-72.
[49]
Ashfaq M, Basra SM, Ashfaq U. Moringa: a miracle plant for agro-forestry. J Agri Soc Sci 2012; 8: 4-12.
[50]
Leone A, Spada A, Battezzati A, Schiraldi A, Aristil J, Bertoli S. Cultivation, genetic, ethnopharmacology, phytochemistry and pharmacology of Moringaoleifera leaves: An overview. Int J Mol Sci 2015; 16(6): 12791-835.
[http://dx.doi.org/10.3390/ijms160612791] [PMID: 26057747]
[51]
Popoola JO, Obembe OO. Local knowledge, use pattern and geographical distribution of Moringa oleifera Lam. (Moringaceae) in Nigeria. J Ethnopharmacol 2013; 150(2): 682-91.
[http://dx.doi.org/10.1016/j.jep.2013.09.043] [PMID: 24096203]
[52]
Agbogidi O, Ilondu E. Moringaoleifera Lam: Its potentials as a food security and rural medicinal item. J Bio Innovation 2012; 1: 156-67.
[53]
Iqbal S, Bhanger M. Effect of season and production location on antioxidant activity of Moringaoleifera leaves grown in Pakistan. J Food Compos Anal 2006; 19: 544-51.
[http://dx.doi.org/10.1016/j.jfca.2005.05.001]
[54]
Karmakar A, Karmakar S, Mukherjee S. Properties of various plants and animals feedstocks for biodiesel production. Bioresour Technol 2010; 101(19): 7201-10.
[http://dx.doi.org/10.1016/j.biortech.2010.04.079] [PMID: 20493683]
[55]
Sánchez-Machado DI, López-Cervantes J, Vázquez NJ. High-performance liquid chromatography method to measure α- and γ-tocopherol in leaves, flowers and fresh beans from Moringa oleifera. J Chromatogr A 2006; 1105(1-2): 111-4.
[http://dx.doi.org/10.1016/j.chroma.2005.07.048] [PMID: 16439255]
[56]
Dachana K, Rajiv J, Indrani D, Prakash J. Effect of dried Moringa (Moringaoleifera Lam) leaves on rheological, microstructural, nutritional, textural and organoleptic characteristics of cookies. J Food Qual 2010; 33: 660-77.
[http://dx.doi.org/10.1111/j.1745-4557.2010.00346.x]
[57]
Mushtaq BS, et al. Characterization of Moringa oleifera leaves and its utilization as value added ingredient in unleavened flat bread (chapatti). J Microbiol Biotechnol Food 2018; 8: 751-5.
[58]
Shakeri A, Hashempur MH, Mojibian M, Aliasl F, Bioos S, Nejatbakhsh F. A comparative study of ranitidine and quince (Cydonia oblonga mill) sauce on gastroesophageal reflux disease (GERD) in pregnancy: A randomised, open-label, active-controlled clinical trial. J Obstet Gynaecol 2018; 38(7): 899-905.
[http://dx.doi.org/10.1080/01443615.2018.1431210] [PMID: 29553843]
[59]
Jabbari M, Daneshfard B, Emtiazy M, Khiveh A, Hashempur MH. Biological effects and clinical applications of dwarf elder (Sambucusebulus L): A review. J Evid Based Complementary Altern Med 2017; 22(4): 996-1001.
[http://dx.doi.org/10.1177/2156587217701322] [PMID: 28397551]
[60]
Hashempur MH, Khademi F, Rahmanifard M, Zarshenas MM. An evidence-based study on medicinal plants for hemorrhoids in Medieval Persia. J Evid Based Complementary Altern Med 2017; 22(4): 969-81.
[http://dx.doi.org/10.1177/2156587216688597] [PMID: 29228790]

Rights & Permissions Print Cite
Article Metrics
40
1
© 2024 Bentham Science Publishers | Privacy Policy