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Current Pharmaceutical Design


ISSN (Print): 1381-6128
ISSN (Online): 1873-4286


Therapeutic Potentials of Adenosine Receptors: The State of The Art

Author(s): Pran Kishore Deb

Volume 25, Issue 26, 2019

Page: [2789 - 2791] Pages: 3

DOI: 10.2174/138161282526191007143942

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Deb PK, Deka S, Borah P, Abed SN, Klotz K-N. Medicinal chemistry and therapeutic potential of agonists, antagonists and allosteric modulators of A1 adenosine receptor: Current status and perspectives. Curr Pharm Des 2019; 25(25): 2697-715.
Al-Attraqchi O, Attimarad M, Venugopala K, Nair A, Al-Attraqchi N. Adenosine A2A receptor as a potential drug target-current status and future perspectives. Curr Pharm Des 2019; 25(25): 2716-40.
Chandrasekaran B, Samarneh S, Jaber AMY, Kassab G, Agrawal N. Therapeutic potentials of A2B adenosine receptor ligands: Current status and perspectives. Curr Pharm Des 2019; 25(25): 2741-71.
Mailavaram RP, Al-Attraqchi O, Kar S, Ghosh S. Current status in the design and development of agonists and antagonists of adenosine A3 receptor as potential therapeutic agents. Curr Pharm Des 2019; 25(25): 2772-87.
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Deb PK, Balakumar C, Rao AR, Roy PP, Roy K. QSAR of adenosine receptor antagonists: Exploring physicochemical requirements for binding of pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives with human adenosine A3 receptor subtype. Bioorg Med Chem Lett 2011; 21: 818-23.
Deb PK, Chandrasekaran B, Mailavaram R, Tekade RK, Jaber AMY. Molecular modeling approaches for the discovery of adenosine A2B receptor antagonists: Current status and future perspectives. Drug Discov Today 2019.
Deb PK. Recent updates in the computer aided drug design strategies for the discovery of agonists and antagonists of adenosine receptors. In: ed. Bentham Science, 2019; pp. 747-749.
Shaik K, Deb PK, Mailavaram RP, et al. 7-Amino-2-aryl/heteroaryl-5-oxo-5,8-dihydro[1,2,4]triazolo[1,5‐a]pyridine‐6‐carbonitriles: Synthesis and adenosine receptor binding studies. Chem Biol Drug Des 2019; 94: 1568-73.
Deb PK, Mailavaram R, Chandrasekaran B, et al. Synthesis, adenosine receptor binding and molecular modelling studies of novel thieno[2,3‐d]pyrimidine derivatives. Chem Biol Drug Des 2018; 91: 962-9.
Chandrasekaran B, Deb PK, Kachler S, Akkinepalli RR, Mailavaram R, Klotz K-N. Synthesis and adenosine receptors binding studies of new fluorinated analogues of pyrido [2,3-d] pyrimidines and quinazolines. Med Chem Res 2018; 27: 756-67.
Balakumar C, Kishore DP, Rao KV, et al. Design, microwave-assisted synthesis and in silico docking studies of new 4H-pyrimido[2, 1-b]benzothiazole-2-arylamino-3-cyano-4-ones as possible adenosine A2B receptor antagonists. Indian J Chem 2012; 51B: 1105-13.
Gessi S, Merighi S, Varani K, Borea PA. Adenosine receptors in health and disease. In: ed. Advances in pharmacology. Elsevier, 2011; pp. 41-75.
Borah P, Deka S, Mailavaram RP, Deb PK. P1 receptor agonists/antagonists in clinical trials-potential drug candidates of the future. Curr Pharm Des 2019; 25(26): 2792-807.
Choudhury H, Chellappan DK, Sengupta P, Pandey M, Gorain B. Adenosine receptors in modulation of central nervous system disorders. Curr Pharm Des 2019; 25(26): 2808-27.
Gorain B, Choudhury H, Yee GS, Bhattamisra SK. Adenosine receptors as novel targets for the treatment of various cancers. Curr Pharm Des 2019; 25(26): 2828-41.
Marwein S, Mishra B, De Chandra U, Acharya PC. Recent progress of adenosine receptor modulators in the development of anticancer chemotherapeutic agents. Curr Pharm Des 2019; 25(26): 2842-58.
Pal Y, Bandyopadhyay N, Pal RS, Ahmed S, Bandopadhyay S. Perspective and potential of A2A and A3 adenosine receptors as therapeutic targets for the treatment of rheumatoid arthritis. Curr Pharm Des 2019; 25(26): 2859-74.
Shakya AK, Naik RR, Almasri IM, Kaur A. Role and function of adenosine and its receptors in inflammation, neuroinflammation, IBS, autoimmune inflammatory disorders, rheumatoid arthritis and psoriasis. Curr Pharm Des 2019; 25(26): 2875-91.
Jamwal S, Mittal A, Kumar P, Alhayani DM, Al-Aboudi A. Therapeutic potential of agonists and antagonists of A1, A2a, A2b and A3 adenosine receptors. Curr Pharm Des 2019; 25(26): 2892-905.

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