The Use of Adenoviral Vectors for Genetic Manipulation and Analysis of Primitive Hematopoietic Cells

Title: The Use of Adenoviral Vectors for Genetic Manipulation and Analysis of Primitive Hematopoietic Cells

Volume: 1 Issue: 3

Author(s): Craig T. Jordan, Elio F. Vanin and Frank C. Marini

Affiliation:

Keywords: Adenoviral Vectors, Primitive Hematopoietic Cells, Hematopoietic Gene, Fiber Protein, antibody redirection, Hybrid Vectors, Capsid Proteins

Abstract: Gene transfer into stem cells has long been studied as a means by which primitive hematopoietic cells could be characterized and manipulated. While a variety of strategies have been attempted, it still remains relatively difficult to perform direct stem cell analysis. In this review, we examine recent studies using adenovirus-based vectors as a means to achieve high-level gene transfer into primitive hematopoietic cell types.

Cite this article as:

Jordan T. Craig, Vanin F. Elio and Marini C. Frank, The Use of Adenoviral Vectors for Genetic Manipulation and Analysis of Primitive Hematopoietic Cells, Current Gene Therapy 2001; 1(3) . https://dx.doi.org/10.2174/1566523013348535