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CNS & Neurological Disorders - Drug Targets


ISSN (Print): 1871-5273
ISSN (Online): 1996-3181

Review Article

Role of Flavonoids in Neurodegenerative Disorders with Special Emphasis on Tangeritin

Author(s): Ambreen Fatima and Yasir Hasan Siddique*

Volume 18, Issue 8, 2019

Page: [581 - 597] Pages: 17

DOI: 10.2174/1871527318666190916141934

Price: $65


Flavonoids are naturally occurring plant polyphenols found universally in all fruits, vegetables and medicinal plants. They have emerged as a promising candidate in the formulation of treatment strategies for various neurodegenerative disorders. The use of flavonoid rich plant extracts and food in dietary supplementation have shown favourable outcomes. The present review describes the types, properties and metabolism of flavonoids. Neuroprotective role of various flavonoids and the possible mechanism of action in the brain against the neurodegeneration have been described in detail with special emphasis on the tangeritin.

Keywords: Flavanoids, tangeritin, neurodegeneration, biosynthetic pathway, polyphenols, flavones.

Graphical Abstract
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