Applications of the in situ Propargyl-Allenyl Isomerization in Organic Synthesis

Author(s): Yanpeng Xing, Yuxiu Wei, Hongwei Zhou

Journal Name: Current Organic Chemistry

Volume 16 , Issue 13 , 2012

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Allenes have been shown to be versatile building blocks in organic synthesis. However, the diversity of the allene chemistry offers a challenging and exquisite task for organic chemists bent on building the suitable allene substrates. A good solution might be propargyl-allenyl isomerization, which means to prepare readily available propargyl substrates. This review focuses on recent progress in the in situ propargyl-allenyl isomerization in organic synthesis, published in 1990 and later.

Keywords: Propargyl-allenyl isomerization, Allene, Cyclization, Base-promotion, Propargyl Ether, coupling–isomerization–Claisen, sulfur (selenium), bis-propargylic sulfides, cycloaddition, nitrogen

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Article Details

Year: 2012
Page: [1594 - 1608]
Pages: 15
DOI: 10.2174/138527212800840973

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