Immune System and Perinatal Outcomes
Pp. 74-87 (14)
Pregnancy represents a semiallograft to a maternal host. To prevent semiallograft rejection,
the maternal immune system dramatically changes to a unique immune system during pregnancy.
Maladaptation of this system could cause implantation failure, recurrent spontaneous abortion,
preeclampsia and preterm delivery. The objective of this report is to review the pathophysiology of
these events in human pregnancy from the aspects of reproductive immunology.
Miscarriage, preeclampsia, pregnancy, preterm labor, reproductive immunology.
Department of Obstetrics and Gynecology, University of Toyama, 2630 Sugitani Toyama-shi, Toyama 930- 0194 Japan