Pregnancy Disorders and Perinatal Outcomes

Indexed in: Book Citation Index, Science Edition (BKCI-S), Web of Science, Scopus, EBSCO.

Pregnancy Disorders and Perinatal Outcomes offers readers insights into knowledge related to maternal habits or disorders that could affect fetal development and lead to disability later in childhood ...
[view complete introduction]

US $

*(Excluding Mailing and Handling)

Immune System and Perinatal Outcomes

Pp. 74-87 (14)

DOI: 10.2174/978160805372811201010074

Author(s): Shigeru Saito


Pregnancy represents a semiallograft to a maternal host. To prevent semiallograft rejection, the maternal immune system dramatically changes to a unique immune system during pregnancy. Maladaptation of this system could cause implantation failure, recurrent spontaneous abortion, preeclampsia and preterm delivery. The objective of this report is to review the pathophysiology of these events in human pregnancy from the aspects of reproductive immunology.


Miscarriage, preeclampsia, pregnancy, preterm labor, reproductive immunology.