Gestational hypertension, preeclampsia, and diabetes are all associated with increased risks of poor maternal
and perinatal outcome. In preeclampsia, exaggerated responses of insulin resistance, altered immune responses and
inflammatory pathway activation are reminiscent of metabolic syndrome, and also are evident in gestational diabetes
mellitus. Poor glycaemic control, preexisting hypertension and diabetic renal disease increase a diabetic woman’s risk for
preeclampsia and associated maternal and fetal complications. In this short review, the possible link between diabetes and
gestational hypertension is discussed.
Keywords: Diabetes, hypertension, pregnancy, insulin resistance, metabolic syndrome, glucose intolerance, pathophysiologic mechanisms, Placental secretion
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