Cinnamic acid is an organic acid occurring naturally in plants that has low toxicity and a broad spectrum of
biological activities. In the search for novel pharmacologically active compounds, cinnamic acid derivatives are important
and promising compounds with high potential for development into drugs. Many cinnamic acid derivatives, especially
those with the phenolic hydroxyl group, are well-known antioxidants and are supposed to have several health benefits due
to their strong free radical scavenging properties. It is also well known that cinnamic acid has antimicrobial activity.
Cinnamic acid derivatives, both isolated from plant material and synthesized, have been reported to have antibacterial,
antiviral and antifungal properties. Acids, esters, amides, hydrazides and related derivatives of cinnamic acid with such
activities are here reviewed.
Keywords: Antifungal, antimicrobial, antioxidant, antiviral, cinnamate, cinnamic acid, cinnamic hydrazide, cinnamide.
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Published on: 28 May, 2012
Page: [749 - 767]