Sperm-Mediated Gene Transfer: Concepts and Controversies

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Sperm-mediated gene transfer (SMGT) represents a novel set of technologies for animal (or in the future, human) genetic modification using the sperm as a vector, as opposed to more traditional ...
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Conclusions

Pp. 125-130 (6)

Kevin R. Smith

Abstract

Several experts in the various fields of SMGT have contributed valuable knowledge to this eBook. This chapter offers a synthesis of the key concepts covered throughout the book, and critically evaluates the current status and controversial aspects of SMGT.

Keywords:

Augmented uptake, Autouptake, En masse GM, Episomal transgene, Gene targeting, Germline modification, Horizontal inheritance, Human artificial chromosome, SMGT scepticism, Zinc-finger nuclease.

Affiliation:

Abertay University, United Kingdom