Sperm-Mediated Gene Transfer: Concepts and Controversies

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Sperm-mediated gene transfer (SMGT) represents a novel set of technologies for animal (or in the future, human) genetic modification using the sperm as a vector, as opposed to more traditional ...
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Pp. 125-130 (6)

Kevin R. Smith


Several experts in the various fields of SMGT have contributed valuable knowledge to this eBook. This chapter offers a synthesis of the key concepts covered throughout the book, and critically evaluates the current status and controversial aspects of SMGT.


Augmented uptake, Autouptake, En masse GM, Episomal transgene, Gene targeting, Germline modification, Horizontal inheritance, Human artificial chromosome, SMGT scepticism, Zinc-finger nuclease.


Abertay University, United Kingdom