An Efficient Synthetic Method for Phenylalanine Containing Crown Ether Ring

Author(s): Xia Tian, Fang Li, Jianrong Han, Xiaoli Zhen, Shouxin Liu

Journal Name: Letters in Organic Chemistry

Volume 9 , Issue 5 , 2012

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An efficient, convenient synthesis method has been introduced for the preparation of phenylalanine containing crown ether ring by nucleophilic substitution, nitrosation and reduction reaction using benzo-crown ether and dimethyl malonate as material. The structures of the product are characterized by 1HNMR, MS and element analysis.

Keywords: Benzo-crown ether, dimethyl malonate, nitrosation, reduction, α-amino acid, synthesis, rotaxanes, catenane, supramolecular, malonate

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Article Details

Year: 2012
Published on: 24 May, 2012
Page: [356 - 359]
Pages: 4
DOI: 10.2174/157017812801264665
Price: $65

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