Abstract
An efficient, convenient synthesis method has been introduced for the preparation of phenylalanine containing crown ether ring by nucleophilic substitution, nitrosation and reduction reaction using benzo-crown ether and dimethyl malonate as material. The structures of the product are characterized by 1HNMR, MS and element analysis.
Keywords: Benzo-crown ether, dimethyl malonate, nitrosation, reduction, α-amino acid, synthesis, rotaxanes, catenane, supramolecular, malonate
Letters in Organic Chemistry
Title:An Efficient Synthetic Method for Phenylalanine Containing Crown Ether Ring
Volume: 9 Issue: 5
Author(s): Xia Tian, Fang Li, Jianrong Han, Xiaoli Zhen and Shouxin Liu
Affiliation:
Keywords: Benzo-crown ether, dimethyl malonate, nitrosation, reduction, α-amino acid, synthesis, rotaxanes, catenane, supramolecular, malonate
Abstract: An efficient, convenient synthesis method has been introduced for the preparation of phenylalanine containing crown ether ring by nucleophilic substitution, nitrosation and reduction reaction using benzo-crown ether and dimethyl malonate as material. The structures of the product are characterized by 1HNMR, MS and element analysis.
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Cite this article as:
Tian Xia, Li Fang, Han Jianrong, Zhen Xiaoli and Liu Shouxin, An Efficient Synthetic Method for Phenylalanine Containing Crown Ether Ring, Letters in Organic Chemistry 2012; 9 (5) . https://dx.doi.org/10.2174/157017812801264665
DOI https://dx.doi.org/10.2174/157017812801264665 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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