Transient tachypnea of the newborn results from delayed clearance of lung fluid and is a common cause of admission of full
term and late preterm infants to neonatal intensive care units. The condition is particularly common after elective cesarean section. Conventional
treatment involves supplemental oxygen, withholding enteral feeds and administration of intravenous fluids and antibiotics.
Rarely, infants require CPAP and mechanical ventilation. Occasionally some babies develop severe hypoxemia and may require high
concentrations of oxygen. The most effective strategy for accelerating reabsorbtion of fetal lung fluid is exogenous glucocorticoids. Potential
therapies for TTN must be based on an understanding of the physiology of normal fetal lung fluid clearence at bith. Furosemide,
racemic epinephrine and inhaled β-agonists have been studied for possible benefit in TTN. The routine administration of these drugs can
not be recommended unless additional data become available.
Keywords: Transient tachypnea, alveolar fluid, furosemide, racemic epinephrine, salbutamol, newborn, lung fluid, preterm infants, intravenous fluids, hypoxemia
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Published on: 23 May, 2012
Page: [3046 - 3049]