Ionic Liquids: A New Strategy in Pharmaceutical Synthesis

Author(s): Tomasz Siodmiak, Michal Piotr Marszall, Anna Proszowska

Journal Name: Mini-Reviews in Organic Chemistry

Volume 9 , Issue 2 , 2012

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The industrial synthesis of pharmaceutical compounds often involves the use of organic solvents. Unfortunately, these reaction media are responsible for organic contaminations in the final product. In recent years, ionic liquids (ILs) have become the “green alternatives” of volatile organic solvents. Thus, the application of ILs instead of conventional reagents offer a new opportunity to solve problems of environmentally harmful solvents. This mini-review discusses a new application of ILs in laboratory-scale pharmaceutical synthesis.

Keywords: Active pharmaceutical ingredient, biocatalytic reaction, green chemistry, ionic liquid, RTILs, antiparasitic drugs, DMAP, NSAIDs, CPPO, BNCT, Prvadoline

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Article Details

Year: 2012
Published on: 08 May, 2012
Page: [203 - 208]
Pages: 6
DOI: 10.2174/157019312800604698

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PDF: 33