Tableting Properties of Assam Bora Rice Starch

Author(s): Mohammad Zaki Ahmad, Sohail Akhter, Ishita Dhiman, Poonam Sharma, Reena Verma, Mahfoozur Rahman, Ananya Rajkumari, Farhan Jalees Ahmad

Journal Name: Drug Delivery Letters

Volume 2 , Issue 1 , 2012

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Starches are used as fillers, binders, and disintegrating agents in the tablet formulation due to their suitable physicochemical as well as mechanical properties. In the present investigation, a study has been done on the compaction properties of Assam Bora rice starch, and their physicochemical properties are evaluated. Assam Bora rice starch exhibit good flow properties. The influences of physical and geometrical properties of starch were evaluated with regard to their compression properties. Further compaction properties of the Assam Bora rice starch were evaluated by density measurement, Heckel and Kawakita equation. The result obtained shows that Assam Bora rice starch deforms mainly by plastic deformation. From the study it has been concluded that Assam Bora rice starch would be more useful in minimizing the problems of lamination and capping especially on high speed tableting machine with short dwelling time for the plastic deformation of material, on the other hand it would be more useful when high tensile strength of tablet is desirable.

Keywords: Assam Bora rice starch, tableting properties, heckel plot, kawakita plot, compaction properties, plastic deformation, tapioca starch, corn starch

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Article Details

Year: 2012
Page: [2 - 7]
Pages: 6
DOI: 10.2174/2210304x11202010002

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