Risk Factors and Atherosclerotic Disease
Pp. 7-21 (15)
S. Novo, G.R. Amoroso, F. Bonura, P. Carità, E. Corrado and G. Novo
In healthy subjects, the Risk Factors (RF) are conditions linked casually to atherosclerosis. They are
related in a logarithmic way to the occurrence of CVE. The atherosclerotic RF can be divided into traditional and
emerging. The traditional and “modifiable” RF include: dislipidemia, diabetes mellitus, hypertension, smoking,
obesity, sedentary, stress, alcohol and diet. Diabetes mellitus is currently considered a “CHD equivalent”. The
emerging RF (studied only for a few years) include: Metabolic Syndrome (MS) (that is characterized by the
presence of various metabolic disorders at the same time in the same subject), biohumoral markers of systemic
inflammation, microalbuminuria and LP (a).
Dislipidemia, smoking, hypertension, diabetes mellitus, lifestyle, obesity, stress, alcohol. Family history,
aging, gender. Metabolic syndrome, inflammation, homocysteine, microalbuminuria, lipoprotein (a), infections.
Department of Internal Medicine and Cardiovascular Diseases, University of Palermo – Italy