Title:Recent Developments in the Analysis of Avermectin and Milbemycin Residues in Food Safety and the Environment
VOLUME: 13 ISSUE: 6
Author(s):Martin Danaher, Wolfgang Radeck, Lucija Kolar, Jemma Keegan and Vesna Cerkvenik-Flajs
Affiliation:Food Safety Department, Teagasc Food Research, Ashtown, Dublin 15, Ireland.
Keywords:Macrocyclic lactones, avermectins, milbemycins, food safety, environmental analysis, animal tissue, milk, fruit,
vegetables, soil, water, faeces
Abstract:A review of the developments on the analysis of residues of avermectins and milbemycins (both macrocyclic
lactones) is presented. The macrocyclic lactones (MLs) are an important class of chemicals, which are used worldwide as
veterinary drugs and as crop protection agents. As a result, residues of MLs are important from both a food safety and
environmental perspective. A review of the developments in ML residues in food was carried out in detail in 2006. As a
result, this paper covers recent developments in the area of food analysis, which are mainly multi-residue assays based on
liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS). A brief coverage of HPLC fluorescence
(HPLC-FLD) based methods is included for completeness. The paper will carry out a comprehensive review of ML
residues in environmental samples. These additional sections are reflective of the growing number of research papers
published on LC-MS/MS and environmental applications in recent years.
