Recent Developments in the Analysis of Avermectin and Milbemycin Residues in Food Safety and the Environment

Author(s): Martin Danaher, Wolfgang Radeck, Lucija Kolar, Jemma Keegan, Vesna Cerkvenik-Flajs

Journal Name: Current Pharmaceutical Biotechnology

Volume 13 , Issue 6 , 2012

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A review of the developments on the analysis of residues of avermectins and milbemycins (both macrocyclic lactones) is presented. The macrocyclic lactones (MLs) are an important class of chemicals, which are used worldwide as veterinary drugs and as crop protection agents. As a result, residues of MLs are important from both a food safety and environmental perspective. A review of the developments in ML residues in food was carried out in detail in 2006. As a result, this paper covers recent developments in the area of food analysis, which are mainly multi-residue assays based on liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS). A brief coverage of HPLC fluorescence (HPLC-FLD) based methods is included for completeness. The paper will carry out a comprehensive review of ML residues in environmental samples. These additional sections are reflective of the growing number of research papers published on LC-MS/MS and environmental applications in recent years.

Keywords: Macrocyclic lactones, avermectins, milbemycins, food safety, environmental analysis, animal tissue, milk, fruit, vegetables, soil, water, faeces

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Article Details

Year: 2012
Published on: 18 April, 2012
Page: [936 - 951]
Pages: 16
DOI: 10.2174/138920112800399068
Price: $65

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