Advances in C-glycosylflavonoid Research

Author(s): Oualid Oualid, Artur M. S. Silva

Journal Name: Current Organic Chemistry

Volume 16 , Issue 7 , 2012

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C-glycosylflavonoids represent a group of oxygen heterocyclic compounds found widespread in a variety of plants. Synthetic organic chemists are now progressively utilizing C-glycosylflavonoid scaffolds due to their high biological potential. The present review deals with advances in C-glycosylflavonoids research, namely establishing a new updated database of the natural occurrence of Cglycosylflavonoids - one hundred and nine new structures have been reported up to 2011. The structural characterization of some novel C-glycosylflavonoids from various plant species is also discussed. The reported organic synthetic routes along with the biosynthetic aspects of C-glycosylflavonoids are also reviewed. Finally the paper underlines the wide range of C-glycosylflavonoid biological activity. The mentioned topics are detailed in particular chapters and are supported in 187 references.

Keywords: Flavonoids, C-glycosylflavonoids, Mono-C-glycosylflavonoids, Di-C-glycosylflavonoids, O-glycosyl-C-glycosylflavonoids, Oacylated- C-glycosylflavonoids, Mass spectrometry, 1D and 2D NMR spectroscopy, Synthesis, Biosynthesis, Metabolism, Biological activity; Antioxidant activity.

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Article Details

Year: 2012
Published on: 04 April, 2012
Page: [859 - 896]
Pages: 38
DOI: 10.2174/138527212800194791

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