Toxicity of Biodegradable Nanoscale Preparations

Author(s): Fan Jian, Yi Zhang, Jing Wang, Kai Ba, Runyi Mao, Wenli Lai, Yunfeng Lin

Journal Name: Current Drug Metabolism

Volume 13 , Issue 4 , 2012

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Abstract:

Nowadays, biodegradable nanoscale preparations such as liposomes, micelles, nanoparticles (NPs), and solid lipid nanoparticles (SLN) have attracted increasing attention from major researchers. Meanwhile the biosafety of the nanomaterials brings more and more attention. Toxicity of the biodegradable nanoscle preparations varies depending on their particle size, shape, surface structure, et al. This article aims to review the toxicity of the above-mentioned nanoscale preparations and the relative methodology. It may be significant for successful use of more nanoscale preparations in clinical practice.

Keywords: Liposomes, micelles, nanoparticles, PLGA, SLN, nanotoxicity

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Article Details

VOLUME: 13
ISSUE: 4
Year: 2012
Page: [440 - 446]
Pages: 7
DOI: 10.2174/138920012800166517
Price: $65

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