Absorption, Pharmacokinetics and Disposition of Biodegradable Nanoscale Preparations

Author(s): Cheng Wang, Jing Wang, Tiezhu Chen, Zhiqiang Luo, Xuemei Yang, Xiongfei Pan, Yunfeng Lin, Zhiyong Qian, Xiaoxiao Cai

Journal Name: Current Drug Metabolism

Volume 13 , Issue 4 , 2012

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Nowadays, biodegradable nanoscale preparations such as liposomes, micelles, nanoparticles (NPs), and solid lipid nanoparticles (SLN) have attracted increasing attention from major researchers. This article aims to review the absorption, pharmacokinetics, distribution properties and toxicity of the above-mentioned nanoscale preparations and the relative methodology. It may be significant for successful use of more nanoscale preparations in clinical practice.

Keywords: Liposomes, micelles, nanoparticles, PLGA, SLN, passive targeting, active targeting

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Article Details

Year: 2012
Page: [429 - 439]
Pages: 11
DOI: 10.2174/138920012800166508
Price: $65

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