Abstract
G-quadruplexes have found increasing potential in applications such as molecular therapeutics, diagnostics, and sensing. As a consequence, small molecules capable of selectively detecting G-quadruplexes have received significant attention in recent literature. Our review here addresses representative advances in the development of luminescent G-quadruplex probes and highlights their potential applications in sensing and imaging.
Keywords: G-quadruplex, DNA, small molecules, luminescent probes, detection, diagnostics, telomere, topologies, propeller, emission
Current Pharmaceutical Design
Title:Luminescent G-quadruplex Probes
Volume: 18 Issue: 14
Author(s): Dik-Lung Ma, Daniel Shiu-Hin Chan, Hui Yang, Hong-Zhang He and Chung-Hang Leung
Affiliation:
Keywords: G-quadruplex, DNA, small molecules, luminescent probes, detection, diagnostics, telomere, topologies, propeller, emission
Abstract: G-quadruplexes have found increasing potential in applications such as molecular therapeutics, diagnostics, and sensing. As a consequence, small molecules capable of selectively detecting G-quadruplexes have received significant attention in recent literature. Our review here addresses representative advances in the development of luminescent G-quadruplex probes and highlights their potential applications in sensing and imaging.
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Cite this article as:
Ma Dik-Lung, Shiu-Hin Chan Daniel, Yang Hui, He Hong-Zhang and Leung Chung-Hang, Luminescent G-quadruplex Probes, Current Pharmaceutical Design 2012; 18 (14) . https://dx.doi.org/10.2174/138161212799958314
DOI https://dx.doi.org/10.2174/138161212799958314 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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