Applications and Case Studies of the Next-Generation Sequencing Technologies in Food, Nutrition and Agriculture

Author(s): George E. Liu

Journal Name: Recent Patents on Food, Nutrition & Agriculture

Volume 1 , Issue 1 , 2009

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The next-generation sequencing technologies are able to produce millions of short sequence reads in a highthroughput, cost-effective fashion. The emergence of these technologies has not only facilitated genome sequencing but also started to change the landscape of life sciences. Here, I survey their major applications ranging from whole-genome sequencing and resequencing, single nucleotide polymorphism (SNP) and structural variation discovery, to mRNA and noncoding RNA profiling and protein-nucleic acid interaction assay. These case studies in structural, functional and comparative genomics, metagenomics, and epigenomics are providing a more complete picture of the genome structures and functions. In the near future, we will witness broad impacts of these next-generation sequencing technologies for solving the complex biological problems in food, nutrition and agriculture. In this article, recent patents based information is also included.

Keywords: Sequencing, resequencing, structural genomics, functional genomics, comparative genomics, metagenomics, epigenomics

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Article Details

Year: 2009
Page: [75 - 79]
Pages: 5
DOI: 10.2174/2212798410901010075

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PDF: 52