Chronotherapeutics is a novel approach in the treatment of various biological disorders. Circadian rhythms are the important factor in the biological cycle through which the drug dosing should be matched with the rhythms of the diseases for the successful treatment of the illness or the disorder. Through this review it shows that different chronotherapeutic approaches have been successfully employed for treating different biological disorders through different formulation methods, and discussion of recent patents.
Keywords: Biological cycle, circadian rhythms, chronotherapeutics, internal clock, time drug delivery, Amplitude, Monolithic Devices, Diffucaps/Surecaps Technology, Pulsatile Drug Delivery System, Pressure-Sensitive Hydrogels
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