Regulatory T Cells in Atopic Dermatitis

Author(s): Naoki Oiso

Journal Name: Recent Patents on Inflammation & Allergy Drug Discovery
Continued as Recent Advances in Inflammation & Allergy Drug Discovery

Volume 4 , Issue 3 , 2010


Atopic dermatitis is one of the most prevalent chronic eczematous inflammatory skin diseases in westernized populations. It is caused by both skin barrier dysfunction and abnormal immunologic response. An imbalance of effector T cells and regulatory T cells is a crucial factor in the initiation of allergic diseases. Recent advances in immunology have revealed the role of regulatory T cells in atopic dermatitis. Treatment of atopic dermatitis consists of restoring and maintaining a sufficient skin barrier and inducing a balanced systemic immune response.

Keywords: Regulatory T cells, atopic dermatitis

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Article Details

Year: 2010
Published on: 01 March, 2012
Page: [244 - 248]
Pages: 5
DOI: 10.2174/187221310793564227
Price: $65

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