Antifolates - Past, Present and Future

Author(s): Aleem Gangjee, Hiteshkumar D. Jain

Journal Name: Current Medicinal Chemistry - Anti-Cancer Agents
Continued as Anti-Cancer Agents in Medicinal Chemistry

Volume 4 , Issue 5 , 2004

Abstract:

This short perspective briefly covers selected aspects of the past, present and future of antifolates in chemotherapy. Both classical and nonclassical analogs currently in the preclinical stage and clinically used agents are covered.

Keywords: thymidylate synthase (ts), dihydrofolate reductase (dhfr), antifolates, classical, nonclassical, inhibitors

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Article Details

VOLUME: 4
ISSUE: 5
Year: 2004
Page: [405 - 410]
Pages: 6
DOI: 10.2174/1568011043352803
Price: $58

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