The Lung in Immune-Mediated Disorder: Rheumatoid Arthritis

Author(s): Antonio Castagnaro, Alfredo Chetta, Emilio Marangio, Maurizio Zompatori, Dario Olivieri

Journal Name: Current Drug Targets - Inflammation & Allergy
Continued as Inflammation & Allergy - Drug Targets

Volume 3 , Issue 4 , 2004


Various pleuro-pulmonary abnormalities are known to complicate vascular collagen diseases, particularly, rheumatoid arthritis. Each component of the respiratory system is affected, either separately or in combination. Although most pulmonary complications appear in an established case of collagen vascular disease, in certain conditions, the lung disease precedes the more typical manifestation. While some complications are asymptomatic and tend to be resolved spontaneously (for e.g. pleuritis and rheumatoid nodules), others may cause severe or fatal conditions (interstitial pneumonia and constrictive bronchiolitis). The incidence of interstitial lung disease is increasing in vascular collagen disease. This may be mainly attributed to the increase use of invasive techniques such as bronchoscopy and video-assisted thoracoscopic surgery and in part due to the use of high resolution computed tomography, and functional pulmonary tests.

Keywords: interstitial lung disease, pleural effusion, rheumatoid arthritis, vasculitis

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Article Details

Year: 2004
Page: [449 - 454]
Pages: 6
DOI: 10.2174/1568010042634532
Price: $58

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