Abstract
The pathogenesis of a number of chronic inflammatory processes can be attributed to prolonged neovascularization. This article reviews recent studies on the vasculature targeting strategies for the treatment of chronic inflammatory diseases. Targeting of the vasculature of inflamed organs could underlie a new pharmacological approach in the treatment of inflammatory diseases by taking advantage of formulations that deliver drugs to blood vessels specifically located at disease sites and to inflammatory cells.
Keywords: antiangiogenesis, chronic inflammatory diseases, vascular targeting
Current Drug Targets - Inflammation & Allergy
Title: Development of Vasculature Targeting Strategies for the Treatment of Chronic Inflammatory Diseases
Volume: 4 Issue: 1
Author(s): Girolamo Ranieri, Roberto Ria, Aldo M. Roccaro, Angelo Vacca and Domenico Ribatti
Affiliation:
Keywords: antiangiogenesis, chronic inflammatory diseases, vascular targeting
Abstract: The pathogenesis of a number of chronic inflammatory processes can be attributed to prolonged neovascularization. This article reviews recent studies on the vasculature targeting strategies for the treatment of chronic inflammatory diseases. Targeting of the vasculature of inflamed organs could underlie a new pharmacological approach in the treatment of inflammatory diseases by taking advantage of formulations that deliver drugs to blood vessels specifically located at disease sites and to inflammatory cells.
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Cite this article as:
Ranieri Girolamo, Ria Roberto, Roccaro M. Aldo, Vacca Angelo and Ribatti Domenico, Development of Vasculature Targeting Strategies for the Treatment of Chronic Inflammatory Diseases, Current Drug Targets - Inflammation & Allergy 2005; 4 (1) . https://dx.doi.org/10.2174/1568010053622966
DOI https://dx.doi.org/10.2174/1568010053622966 |
Print ISSN 1568-010X |
Publisher Name Bentham Science Publisher |
Online ISSN 1568-010X |
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