Novel Adjuvants for Vaccines

Author(s): Giampietro Corradin, Giuseppe Del Giudice

Journal Name: Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents
Continued as Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry

Volume 4 , Issue 2 , 2005


The review covers basic recent discoveries on the mechanism of action of adjuvants, which have been developed in the last decade. In particular, it focuses on the activation of TOLL like receptors and subsequent release of pro-inflammatory lymphokines (innate immunity), which, in turn, are thought to activate antigen specific responses (adaptive immunity). Given the number of novel adjuvants available to researchers, we limited the scope of the review to those adjuvants which are routinely used in our laboratories and of which we have first hand information.

Keywords: adjuvant, vaccine, t cell, antibody, delivery, tlr

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Article Details

Year: 2005
Page: [185 - 191]
Pages: 7
DOI: 10.2174/1568014053507113
Price: $58

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