BioArena Studies: Unique Function of Endogenous Formaldehyde and Ozone in the Antibiotic Effect – A Review

Title: BioArena Studies: Unique Function of Endogenous Formaldehyde and Ozone in the Antibiotic Effect – A Review

Volume: 8 Issue: 1

Author(s): Erno Tyihak, Agnes M. Moricz and Peter G. Ott

Affiliation:

Keywords: Antibiotic, BioArena, cell proliferation, direct bioautography, formaldehyde, hydroxymethyl group, OPLC, ozone, troposphere, drug

Abstract: The investigations demonstrated clearly a unique function and role of endogenous formaldehyde (HCHO) and ozone (O3) in the antibiotic effect of diverse molecules having different chemical structure. Elimination of HCHO and/or O3 from the layer chromatographic spots resulted in a decrease in the antimicrobial activity. On the basis of detection and measure of endogenous HCHO and O3 BioArena enables to both direct isolation and biological evaluation of new bioactive compounds.

Cite this article as:

Tyihak Erno, M. Moricz Agnes and G. Ott Peter, BioArena Studies: Unique Function of Endogenous Formaldehyde and Ozone in the Antibiotic Effect – A Review, Medicinal Chemistry 2012; 8 (1) . https://dx.doi.org/10.2174/157340612799278388