Recent Progress Towards Transition-Metal-Catalyzed Direct Arylation of Heteroarenes

Author(s): Ye-Xiang Su, Li-Ping Sun

Journal Name: Mini-Reviews in Organic Chemistry

Volume 9 , Issue 1 , 2012

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In this short review, the direct intermolecular cross-coupling reactions of heteroarenes with aryl (pseudo)halides catalyzed by transition metals via C-H bond cleavage in recent years are described. The fundamental emphasis has been given to the synthetic aspects of different intermolecular direct cross-coupling reaction. Much attention is drawn to the palladium-catalyzed arylation reactions due to their important utility at present. Meanwhile, the procedures employed other transition metals are also presented.

Keywords: Aryl (pseudo)halides, C-H activation/functionalization, direct arylation, heteroarenes, transition metals, pallidium complexes, nongenotoxicity, thiazole arylation, oxazole ring system, electron rich

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Article Details

Year: 2012
Page: [87 - 117]
Pages: 31
DOI: 10.2174/157019312799079884

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