Labdane Diterpenes with Highly Functionalized B Rings

Author(s): I.S. Marcos, L. Castaneda, P. Basabe, D. Diez, J.G. Urones

Journal Name: Mini-Reviews in Organic Chemistry

Volume 9 , Issue 1 , 2012

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In this review, the natural source, structure, biological activities and the synthesis of labdanes diterpenes with highly functionalized B rings, described to date are shown. The structures for these compounds have been classified taking into account the number of oxygenated positions of the B ring. In this manner the classification has 7 groups of deoxygenated labdanes, 6 of trioxygenated and one group of the tetraoxygenated ones.

Keywords: Bioactivities, diterpenes, forskolin, labdanes, synthesis, terpenes, functionalized B-rings, adenylate cyclase, nitric oxide, erigerol

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Article Details

Year: 2012
Page: [54 - 86]
Pages: 33
DOI: 10.2174/157019312799080044

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PDF: 38